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(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Sevilla, Spain and 212 other locations
The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...
Phase 2
Sevilla, Spain and 32 other locations
The purpose of this study is to measure tumor response to treatment with ompenaclid (RGX-202) in patients with previously treated RAS mutant advanced...
Phase 2
Sevilla, Spain and 27 other locations
and pembrolizumab) given together for the treatment of colorectal cancer that:is metastatic (spread to other parts of the body);has the cond...
Phase 2
Sevilla, Spain and 108 other locations
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor...
Phase 1
Sevilla, Spain and 63 other locations
plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...
Phase 3
Sevilla, Spain and 152 other locations
To assess:efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification,...
Phase 2
Sevilla, Spain and 90 other locations
with standard chemotherapy for the potential treatment of colorectal cancer that:has spread to other parts of the body (metastatic);has a ce...
Phase 3
Sevilla, Spain and 409 other locations
is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer...
Phase 1, Phase 2
Sevilla, Spain and 46 other locations
The main purpose of this study is to demonstrate the superiority of S 95005 in combination with bevacizumab over capecitabine in combination with bev...
Phase 3
Sevilla, Spain and 189 other locations
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