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(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Toronto, Ontario, Canada and 212 other locations
The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...
Phase 2
Toronto, Ontario, Canada and 32 other locations
and pembrolizumab) given together for the treatment of colorectal cancer that:is metastatic (spread to other parts of the body);has the cond...
Phase 2
Toronto, Ontario, Canada and 108 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Toronto, Ontario, Canada and 827 other locations
in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...
Phase 1
Toronto, Ontario, Canada and 12 other locations
A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm teste...
Phase 1
Toronto, Ontario, Canada and 17 other locations
This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET...
Phase 1, Phase 2
Toronto, Ontario, Canada and 25 other locations
To assess:efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification,...
Phase 2
Toronto, Canada and 90 other locations
Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus...
Phase 3
Toronto, Ontario, Canada and 308 other locations
with standard chemotherapy for the potential treatment of colorectal cancer that:has spread to other parts of the body (metastatic);has a ce...
Phase 3
Toronto, Ontario, Canada and 409 other locations
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