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Find clinical trials for Colon Cancer in Toronto, ON

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Adenocarcinoma
Lung Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Toronto, ON, CAN:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: FOLFOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Toronto, Ontario, Canada and 212 other locations

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...

Active, not recruiting
Microsatellite Unstable Colorectal Cancer
Microsatellite Stable Colorectal Cancer
Drug: Ipilimumab
Drug: Daratumumab

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Toronto, Ontario, Canada and 32 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:is metastatic (spread to other parts of the body);has the cond...

Enrolling
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 101 other locations

in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...

Enrolling
Anal Cancer
Esophagogastric Cancer
Drug: KFA115
Drug: pembrolizumab

Phase 1

Novartis
Novartis

Toronto, Ontario, Canada and 9 other locations

A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm teste...

Active, not recruiting
BRAF V600 Colorectal Cancer
Drug: TNO155
Biological: Spartalizumab

Phase 1

Novartis
Novartis

Toronto, Ontario, Canada and 17 other locations

This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Toronto, Ontario, Canada and 25 other locations

To assess:efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification,...

Enrolling
Colon Cancer
Lung Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Toronto, Canada and 90 other locations

Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Drug: mFOLFOX6 Regimen

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Toronto, Ontario, Canada and 308 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:has spread to other parts of the body (metastatic);has a ce...

Enrolling
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Toronto, Ontario, Canada and 408 other locations

is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer...

Active, not recruiting
Colorectal Cancer
Colorectal Carcinoma
Drug: Regorafenib
Drug: Trametinib

Phase 1, Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Toronto, Ontario, Canada and 46 other locations

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