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Find clinical trials for Colon Cancer in Toronto, ON

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Neoplasm Metastasis
Adenocarcinoma

Colon Cancer trials near Toronto, ON, CAN:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Toronto, Canada and 250 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:* is metastatic (spread to other parts of the body);* has the ...

Active, not recruiting
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 111 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Toronto, Ontario, Canada and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Toronto, Ontario, Canada and 904 other locations

in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...

Enrolling
Anal Cancer
Triple Negative Breast Neoplasms
Drug: pembrolizumab
Drug: KFA115

Phase 1

Novartis
Novartis

Toronto, Ontario, Canada and 12 other locations

Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET...

Enrolling
Brain Tumor
Colon Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Toronto, Canada and 90 other locations

of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

Phase 2

BioNTech
BioNTech

Toronto, Canada and 117 other locations

in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...

Enrolling
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: Oral repotrectinib (TPX-0005)

Phase 1, Phase 2

Turning Point Therapeutics
Turning Point Therapeutics

Toronto, Ontario, Canada and 154 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Toronto, Ontario, Canada and 408 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Toronto, Ontario, Canada and 393 other locations

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