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Find clinical trials for COVID-19 in Boston, MA

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Related conditions:

Infections
Coronavirus Infections
Communicable Diseases
Human Influenza
Post-Acute COVID-19 Syndrome
Pneumonia
Syndrome

COVID-19 trials near Boston, MA, USA:

Defibrotide for the Treatment of Severe COVID-19

The goal of this study is to evaluate the safety and feasibility of defibrotide in COVID-19 pneumonia....

Enrolling
Covid19
Drug: Defibrotide

Phase 2

Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States

A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults

The proposed trial will obtain preliminary data on the feasibility of studying RTB101 as compared to placebo for COVID-19 post-expo...

Active, not recruiting
Covid19
Drug: Placebo
Drug: RTB101

Phase 2

resTORbio

Roslindale, Massachusetts, United States and 1 other location

A Study of mRNA-1283 Injection Compared With mRNA-1273 Injection in Participants ≥12 Years of Age to Prevent COVID-19 (NextCOVE)

The purpose of this study (Part 1 and Part 2) is to evaluate the relative vaccine efficacy (rVE), safety, reactogenicity, and immunogenicity of mRNA-...

Active, not recruiting
COVID-19
Biological: mRNA-1283.222
Biological: mRNA-1273.815

Phase 3

Moderna
Moderna

Boston, Massachusetts, United States and 217 other locations

Study of a Combination Vaccine Comprised of Different Recombinant Spike Antigen Levels of a Matrix-M Adjuvanted Recombinant COVID-19 Vaccine and Recombinant Influenza Vaccine in Adult Participants 50 Years of Age and Older

States. The purpose of the study is to assess the safety and immunogenicity of recombinant influenza vaccine (RIV) + adjuvanted recombinant COVID...

Enrolling
COVID-19 Immunization
Influenza Immunization
Biological: RIV + rC19 (dose 3)
Biological: RIV + rC19 (dose 2)

Phase 1, Phase 2

Sanofi
Sanofi

Malden, Massachusetts, United States and 11 other locations

Evaluation of Home Use COVID-19 Frequent Antigen Testing and Data Reporting (Chelsea_MA)

. There are no established monitoring nationwide protocols for COVID-19 prevention of infection. Due to the lack of such protocols,-...

Enrolling
COVID-19 Respiratory Infection
Diagnostic Test: SARS CoV-2 antigen tests

Phase 1

IDX20

Chelsea, Massachusetts, United States

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

be tolerated for treatment of pregnant women with mild or moderate COVID-19 compared to non-pregnant women with mild or moderate CO-...

Enrolling
COVID-19
Drug: nirmatrelvir
Drug: ritonavir

Phase 1

Pfizer
Pfizer

Boston, Massachusetts, United States and 32 other locations

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

seek to enroll immunocompromised patients with Lower Tract parainfluenza infection.It also contains a sub-study to enroll patients with severe COVID...

Enrolling
COVID-19
Parainfluenza
Drug: DAS181 COVID-19
Drug: DAS181

Phase 3

Ansun Biopharma

Boston, Massachusetts, United States and 66 other locations

Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study

known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19.The aim of the Phase I/III study (Parent Study) will -...

Active, not recruiting
COVID-19, SARS-CoV-2
Biological: AZD3152 (Sub-study)
Biological: Placebo (Parent study Sentinel Safety Cohort)

Phase 2, Phase 3

AstraZeneca
AstraZeneca

Boston, Massachusetts, United States and 214 other locations

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies ...

Enrolling
COVID-19
SARS-CoV-2 Virus
Biological: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 10 microgram dose
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose

Phase 2, Phase 3

BioNTech
BioNTech

Boston, Massachusetts, United States and 114 other locations

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID...

Enrolling
COVID-19
Drug: nirmatrelvir
Drug: ritonavir

Phase 2, Phase 3

Pfizer
Pfizer

Boston, Massachusetts, United States and 109 other locations

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