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Find clinical trials for COVID-19 in Charlotte, NC

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Related conditions:

Infections
Communicable Diseases
Coronavirus Infections
Pneumonia
Post-Acute COVID-19 Syndrome
Human Influenza
Syndrome

COVID-19 trials near Charlotte, NC, USA:

A Study to Investigate the Prevention of COVID-19 withVYD222 in Adults With Immune Compromise and in Participants Aged 12 Years or Older Who Are at Risk of Exposure to SARS-CoV-2

A study to investigate the prevention of COVID-19 with VYD222 in adults with immune compromise and in participants aged 12 years or...

Active, not recruiting
COVID-19
SARS-CoV-2
Drug: VYD222 (pemivibart)
Drug: Normal saline

Phase 3

Invivyd

Salisbury, North Carolina, United States and 17 other locations

A Study of mRNA-1283.222 Injection Compared With mRNA-1273.222 Injection in Participants ≥12 Years of Age to Prevent COVID-19 (NextCOVE)

The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...

Active, not recruiting
COVID-19
Biological: mRNA-1273.222
Biological: mRNA-1283.222

Phase 3

Moderna
Moderna

Monroe, North Carolina, United States of America and 217 other locations

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Combined Modified RNA Vaccine Candidate Against COVID-19 and Influenza.

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vacci-...

Active, not recruiting
COVID-19
Influenza
Biological: COVID-19 Vaccine
Biological: Influenza and COVID-19 Combination A

Phase 3

BioNTech
BioNTech

Monroe, North Carolina, United States of America and 159 other locations

PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19

This is a phase 2 double-blind, randomized study of PBI-0451(Pomotrelvir) in nonhospitalized symptomatic adults with COVID-19. PBI--...

Active, not recruiting
COVID-19
Drug: Placebo
Drug: PBI-0451 (Pomotrelvir)

Phase 2

Pardes Biosciences

Denver, North Carolina, United States of America and 54 other locations

Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study

known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19.The aim of the Phase I/III study (Parent Study) will -...

Active, not recruiting
COVID-19, SARS-CoV-2
Biological: AZD3152 (Sub-study)
Biological: Placebo (Parent study Sentinel Safety Cohort)

Phase 2, Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 214 other locations

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies ...

Enrolling
COVID-19
SARS-CoV-2 Virus
Biological: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 10 microgram dose
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose

Phase 2, Phase 3

BioNTech
BioNTech

Charlotte, North Carolina, United States and 114 other locations

Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines (COVID-19)

This is a Phase 2/3, randomized, double-blind study to evaluate the safety and immunogenicity of different booster dose levels of the monovalent seve...

Active, not recruiting
COVID-19
Biological: NVX-CoV2601 (5μg)
Biological: NVX-CoV2601 (35μg)

Phase 2, Phase 3

Novavax
Novavax

Gaffney, South Carolina, United States and 49 other locations

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

The study is divided into 2 parts: Part 1 and Part 2. The purpose of Part 1 of this study is to generate sufficient safety, reactogenicity, and immun...

Active, not recruiting
Influenza
SARS-CoV-2
Biological: COVID-19 Vaccine 2
Biological: Investigational COVID-19 Vaccine 1

Phase 1, Phase 2

Moderna
Moderna

Charlotte, North Carolina, United States and 68 other locations

Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE)

The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr...

Enrolling
Allogeneic Hematopoietic Cell Transplant
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)
Biological: tabelecleucel

Phase 3

Atara Biotherapeutics

Charlotte, North Carolina, United States and 70 other locations

A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease (Clarity AD)

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiorit...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: Lecanemab

Phase 3

Eisai
Eisai

Charlotte, North Carolina, United States and 246 other locations

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