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The purpose of this study (Part 1 and Part 2) is to evaluate the relative vaccine efficacy (rVE), safety, reactogenicity, and immunogenicity of mRNA-...
Phase 3
Cleveland, Ohio, United States and 217 other locations
study is to determine if the study drug baricitinib is effective and safe in hospitalized pediatric participants with Coronavirus disease 2019 (COVID...
Phase 3
Cleveland, Ohio, United States and 19 other locations
This study is an adaptive, randomized, double blind, platform trial evaluating promising investigational products (IP) for safety and efficacy as ear...
Phase 2
Cleveland, Ohio, United States and 5 other locations
(SARS-CoV2) vaccine tablet VXA-CoV2-3.1 compared to a currently recommended vaccine for the prevention of symptomatic Coronavirus Disease 2019 (COVID...
Phase 2
Beachwood, Ohio, United States and 144 other locations
known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19.The aim of the Phase I/III study (Parent Study) will -...
Phase 2, Phase 3
Westlake, Ohio, United States and 214 other locations
seek to enroll immunocompromised patients with Lower Tract parainfluenza infection.It also contains a sub-study to enroll patients with severe COVID...
Phase 3
Cleveland, Ohio, United States and 59 other locations
study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID...
Phase 2, Phase 3
Cleveland, Ohio, United States and 108 other locations
studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies ...
Phase 2, Phase 3
Cleveland, Ohio, United States and 114 other locations
to investigate the safety, efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and immunogenicity of efgartigimod in participants with post-COVID...
Phase 2
Cleveland, Ohio, United States and 8 other locations
This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary...
Phase 2, Phase 3
South Euclid, Ohio, United States of America and 94 other locations
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