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The Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19 (MATIS) study is a two-stage, open-label, randomised controlled -...
Phase 1, Phase 2
London, United Kingdom
COVID-19 (SARS-CoV2 virus) was declared a global pandemic by the WHO on 11th March 2020. Currently there are no drugs proven to pre-...
Phase 2, Phase 3
London, United Kingdom and 44 other locations
This study will test the COVID-19 vaccine candidate AZD1222 to investigate its safety, tolerability and capability of boosting immu-...
Phase 1
London, United Kingdom
The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...
Phase 3
London, United Kingdom and 217 other locations
known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19.The aim of the Phase I/III study (Parent Study) will -...
Phase 2, Phase 3
London, United Kingdom and 214 other locations
prioritized to receive early treatment for COVID-19 as they are at high risk of disease progression, and because of their potentia...
Phase 4
London, United Kingdom and 6 other locations
This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary...
Phase 2, Phase 3
London, United Kingdom and 95 other locations
This Phase 2/3 study is a multi-portion design to confirm that the chosen formulation and dosing regimen of CoVLP has an acceptable immunogenicity an...
Phase 2, Phase 3
London, United Kingdom and 90 other locations
A multi-part study of ALG-097558 to evaluate safety, tolerability, pharmacokinetics and drug-drug interaction potential after single and multiple dos...
Phase 1
London, United Kingdom
An Exploratory Study to Establish the Dose, Safety and Pathogenicity of a SARS-CoV-2 Omicron Challenge Strain (BA.5) in Healthy Participants 18 to 30...
Early Phase 1
London, United Kingdom
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