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The Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19 (MATIS) study is a two-stage, open-label, randomised controlled -...
Phase 1, Phase 2
London, United Kingdom
COVID-19 (SARS-CoV2 virus) was declared a global pandemic by the WHO on 11th March 2020. Currently there are no drugs proven to pre-...
Phase 2, Phase 3
London, United Kingdom and 44 other locations
This study will test the COVID-19 vaccine candidate AZD1222 to investigate its safety, tolerability and capability of boosting immu-...
Phase 1
London, United Kingdom
The purpose of this study (Part 1 and Part 2) is to evaluate the relative vaccine efficacy (rVE), safety, reactogenicity, and immunogenicity of mRNA-...
Phase 3
London, United Kingdom and 217 other locations
known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19.The aim of the Phase I/III study (Parent Study) will -...
Phase 2, Phase 3
London, United Kingdom and 214 other locations
study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID...
Phase 2, Phase 3
London, United Kingdom and 109 other locations
This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary...
Phase 2, Phase 3
London, United Kingdom and 94 other locations
This Phase 2/3 study is a multi-portion design to confirm that the chosen formulation and dosing regimen of CoVLP has an acceptable immunogenicity an...
Phase 2, Phase 3
London, United Kingdom and 90 other locations
A multi-part study of ALG-097558 to evaluate safety, tolerability, pharmacokinetics and drug-drug interaction potential after single and multiple dos...
Phase 1
London, United Kingdom
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19...
Phase 4
Cambridge, United Kingdom and 7 other locations
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