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The study is a prospective, randomized, 52-week double-blind, placebo-controlled, multicenter trial in subjects with T1D followed by a 2-year safety...
Phase 2
Chapel Hill, North Carolina, United States and 22 other locations
blood sugar that sometimes happens when injecting insulin in Type 1 diabetes patients. Participants will use continuous glucose monitoring t...
Phase 2
Chapel Hill, North Carolina, United States and 26 other locations
Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...
Phase 2
Raleigh, North Carolina, United States and 56 other locations
OPL-0401-201 is a multicenter study to investigate the safety and efficacy of OPL-0401 in patients with diabetes mellitus (DM) with diabetic...
Phase 2
Wake Forest, North Carolina, United States of America and 24 other locations
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...
Phase 3
Chapel Hill, North Carolina, United States and 66 other locations
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States and 5 other locations
implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States
This is a Phase 3 trial of cadisegliatin as adjunctive therapy to insulin in participants with Type 1 Diabetes Mellitus....
Phase 3
Chapel Hill, North Carolina, United States of America and 19 other locations
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes...
Phase 3
Chapel Hill, North Carolina, United States and 81 other locations
digital therapeutic intended to help patients with type 2 diabetes improve their glycemic control, will lower hemoglobin A1c (HbA1c) compare...
Durham, North Carolina, United States and 2 other locations
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