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The study is a prospective, randomized, 52-week double-blind, placebo-controlled, multicenter trial in subjects with T1D followed by a 2-year safety...
Phase 2
Chapel Hill, North Carolina, United States and 22 other locations
COORDINATE-Diabetes is a cluster-randomized clinical trial to test the effectiveness of an innovative, clinic-level educational intervention...
Burlington, North Carolina, United States and 43 other locations
blood sugar that sometimes happens when injecting insulin in Type 1 diabetes patients. Participants will use continuous glucose monitoring t...
Phase 2
Chapel Hill, North Carolina, United States and 18 other locations
Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...
Phase 2
Raleigh, North Carolina, United States and 56 other locations
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...
Phase 3
Chapel Hill, North Carolina, United States and 46 other locations
Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled on one or more glucose lowering agent...
Durham, North Carolina, United States and 64 other locations
OPL-0401-201 is a multicenter study to investigate the safety and efficacy of OPL-0401 in patients with diabetes mellitus (DM) with diabetic...
Phase 2
Wake Forest, North Carolina, United States of America and 24 other locations
of hypercortisolism in a population with difficult to control type 2 diabetes (T2D) (hemoglobin A1c ≥7.5%) despite receiving standard-of-car...
Phase 4
Chapel Hill, North Carolina, United States and 35 other locations
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes...
Phase 3
Chapel Hill, North Carolina, United States and 49 other locations
digital therapeutic intended to help patients with type 2 diabetes improve their glycemic control, will lower hemoglobin A1c (HbA1c) compare...
Durham, North Carolina, United States and 2 other locations
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