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The study is a prospective, randomized, 52-week double-blind, placebo-controlled, multicenter trial in subjects with T1D followed by a 2-year safety...
Phase 2
Chapel Hill, North Carolina, United States and 22 other locations
blood sugar that sometimes happens when injecting insulin in Type 1 diabetes patients. Participants will use continuous glucose monitoring t...
Phase 2
Chapel Hill, North Carolina, United States and 26 other locations
Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...
Phase 2
Raleigh, North Carolina, United States and 56 other locations
OPL-0401-201 is a multicenter study to investigate the safety and efficacy of OPL-0401 in patients with diabetes mellitus (DM) with diabetic...
Phase 2
Wake Forest, North Carolina, United States of America and 24 other locations
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...
Phase 3
Chapel Hill, North Carolina, United States and 66 other locations
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States and 5 other locations
implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes...
Phase 3
Chapel Hill, North Carolina, United States and 81 other locations
digital therapeutic intended to help patients with type 2 diabetes improve their glycemic control, will lower hemoglobin A1c (HbA1c) compare...
Durham, North Carolina, United States and 2 other locations
The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increas...
Phase 3
Durham, North Carolina, United States and 654 other locations
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