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Find clinical trials for Diabetes in Toronto, ON

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Related conditions:

Type 2 Diabetes Mellitus
Diabetes Mellitus
Obesity
Type 1 Diabetes Mellitus
Overweight
Diabetic Foot
Foot Ulcer

Diabetes trials near Toronto, ON, CAN:

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease (SUGARNSALT)

inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 ...

Enrolling
Diabetic Nephropathies
Diabetes Mellitus Type 1
Drug: Placebo
Drug: Sotagliflozin

Phase 3

Alessandro Doria

Toronto, Ontario, Canada and 18 other locations

ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion.

This study will evaluate the safety and performance of ENCRT-103-hPI, which is a cargo of primary islets inside Encellin's ENC-103-CED. The 103 offer...

Begins enrollment in 4 months
Type 1 Diabetes
Device: ENCRT-103-hPI encompasses the ENC-103 device, which will be implanted once loaded with primary islet cargo.

Phase 1

Encellin

Toronto, Ontario, Canada and 1 other location

Clinical Phase II/III Trial of Ustekinumab to Treat Type 1 Diabetes (UST1D2)

In type 1 diabetes (T1D), immune defense cells in the body attack and destroy insulin-producing beta cells leaving affected people with a li...

Active, not recruiting
Type 1 Diabetes Mellitus
Drug: Ustekinumab
Drug: Placebo

Phase 2, Phase 3

University of British Columbia
University of British Columbia

Toronto, British Columbia, Canada and 1 other location

New

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight (SELENE 2)

The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will be compared to pl...

Not yet enrolling
Diabetes Mellitus, Type 2
Obesity or Overweight
Drug: AZD6234
Drug: Placebo

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 217 other locations

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes (SURPASS-EARLY)

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing ...

Active, not recruiting
Type 2 Diabetes
Drug: Antihyperglycemic medication
Drug: Tirzepatide

Phase 4

Lilly
Lilly

Stouffville, Ontario, Canada and 89 other locations

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus (SELENE 3)

The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will be compared to pl...

Not yet enrolling
With/Without Diabetes Mellitus, Type 2
Weight-Related Comorbidity
Drug: AZD6234
Drug: Placebo

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 87 other locations

A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)

study medicine to help adults with obesity or overweight and type 2 diabetes lose weight. Being overweight or obese means carrying too much ...

Active, not recruiting
Diabetes, Type 2
Type 2 Diabetes
Drug: PF-08653944
Other: Placebo

Phase 3

Pfizer
Pfizer

Toronto, Ontario, Canada and 183 other locations

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

This is a multicenter, randomized, placebo-controlled, 2-part study to evaluate the safety and efficacy of AT-001 in adult patients (N=675) with Diabetic...

Active, not recruiting
Diabetic Cardiomyopathies
Drug: AT-001
Drug: Placebo

Phase 3

Applied Therapeutics

Toronto, Ontario, Canada and 78 other locations

Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)

control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes...

Active, not recruiting
Diabetes Mellitus, Type 1
Drug: Ritlecitinib
Drug: Abrocitinib 200 MG Oral Tablet

Phase 2

National Institutes of Health (NIH)
National Institutes of Health (NIH)

Toronto, Ontario, Canada and 29 other locations

A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy

This study will look at the effects of CagriSema in people with both type 2 diabetes and painful diabetic peripheral neuropathy, co...

Active, not recruiting
Diabetes Mellitus, Type 2
Diabetic Peripheral Neuropathy
Drug: CagriSema (Cagrilintide B and Semaglutide I)
Drug: Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)

Phase 2

Novo Nordisk
Novo Nordisk

Toronto, Ontario, Canada and 55 other locations

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