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Find clinical trials for Diabetes in Toronto, ON

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Related conditions:

Diabetes Mellitus
Type 2 Diabetes Mellitus
Type 1 Diabetes Mellitus
Diabetic Foot
Foot Ulcer
Obesity
Ulcer

Diabetes trials near Toronto, ON, CAN:

Empagliflozin and the Preservation of Beta-cell Function in Women With Recent Gestational Diabetes (EMPA post-GDM)

Double-blind, parallel arm, randomized controlled trial, in which non-lactating women with recent GDM who are between 6 to 36 months postpartum to be...

Enrolling
Gestational Diabetes
Drug: Empagliflozin 10 MG
Drug: Placebo oral capsule

Phase 3

Mount Sinai Hospital, Canada

Toronto, Ontario, Canada

inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 ...

Not yet enrolling
Diabetic Nephropathies
Diabetes Mellitus Type 1
Drug: Sotagliflozin
Drug: Placebo

Phase 3

Alessandro Doria

Toronto, Ontario, Canada and 18 other locations

In type 1 diabetes (T1D), immune defense cells in the body attack and destroy insulin-producing beta cells leaving affected people with a li...

Enrolling
Type 1 Diabetes Mellitus
Drug: Ustekinumab
Drug: Placebo

Phase 2, Phase 3

University of British Columbia
University of British Columbia

Toronto, British Columbia, Canada and 1 other location

The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...

Enrolling
Type 2 Diabetes Mellitus
Chronic Kidney Diseases
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Oshawa, Ontario, Canada and 45 other locations

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing ...

Active, not recruiting
Type 2 Diabetes
Drug: Antihyperglycemic medication
Drug: Tirzepatide

Phase 4

Lilly
Lilly

Stouffville, Ontario, Canada and 89 other locations

This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medic...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Toronto, Ontario, Canada and 174 other locations

This is a multicenter, randomized, placebo-controlled, 2-part study to evaluate the safety and efficacy of AT-001 in adult patients (N=675) with Diabetic...

Active, not recruiting
Diabetic Cardiomyopathies
Drug: AT-001
Drug: Placebo

Phase 3

Applied Therapeutics

Toronto, Ontario, Canada and 78 other locations

The purpose of the study is to evaluate the safety, tolerability, and efficacy of VX-264 in participants with type 1 diabetes (T1D)....

Enrolling
Type 1 Diabetes
Drug: VX-264

Phase 1, Phase 2

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Toronto, Canada and 14 other locations

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increas...

Active, not recruiting
Type 2 Diabetes Mellitus
Drug: Tirzepatide
Drug: Dulaglutide

Phase 3

Lilly
Lilly

Toronto, Ontario, Canada and 651 other locations

The aim of this study is to test the hypothesis that the effects on albuminuria of combination treatment with the endothelin receptor antagonist zibo...

Invitation-only
Chronic Kidney Diseases
Drug: Zibotentan
Drug: Dapagliflozin and Zibotentan

Phase 2

University Medical Center Groningen (UMCG)

Toronto, Ontario, Canada and 6 other locations

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