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This study seeks to determine the effectiveness of Rucaparib as maintenance therapy for metastatic and recurrent endometrial cancer...
Phase 2
Aurora, Colorado, United States
Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor...
Phase 1
Aurora, Colorado, United States and 20 other locations
IMGN151-1001 is a Phase 1, first in human, open-label dose-escalation and expansion study in adult patients with recurrent endometrial cancer...
Phase 1
Aurora, Colorado, United States and 8 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Aurora, Colorado, United States and 202 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Aurora, Colorado, United States and 16 other locations
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors....
Phase 1
Denver, Colorado, United States and 7 other locations
Phase.* Cohort A: Advanced or Metastatic Triple Negative Breast Cancer (TNBC) (IO-treated)* Cohort B: Advanced or Metastatic Triple Negative ...
Phase 1, Phase 2
Aurora, Colorado, United States and 15 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Aurora, Colorado, United States and 66 other locations
will also assess the clinical benefit of combination therapy in participants with advanced unresectable and/or metastatic ICI refractory solid tumors...
Phase 1, Phase 2
Aurora, Colorado, United States and 16 other locations
preliminary antitumor activity of NKT3447 in adult subjects with cyclin E1 (CCNE1) amplified ovarian cancer at the RDEs selected in Dose Es...
Phase 1
Denver, Colorado, United States and 7 other locations
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