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(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Aurora, Colorado, United States and 202 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Aurora, Colorado, United States and 188 other locations
to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...
Phase 2
Aurora, Colorado, United States and 89 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Aurora, Colorado, United States and 16 other locations
aggressive and challenging to treat. The study will test whether GSK4418959 alone or in combination with a PD-1 inhibitor agent can decrease tumor...
Phase 1, Phase 2
Denver, Colorado, United States and 21 other locations
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors....
Phase 1
Denver, Colorado, United States and 50 other locations
This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer...
Phase 1, Phase 2
Aurora, Colorado, United States and 59 other locations
antibody, in participants with platinum-refractory/resistant ovarian cancer (PRROC) and other advanced CLDN6-positive solid tumors ...
Phase 1
Denver, Colorado, United States and 12 other locations
The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.
Phase 1
Denver, Colorado, United States and 26 other locations
will also assess the clinical benefit of combination therapy in participants with advanced unresectable and/or metastatic ICI refractory solid tumors...
Phase 1, Phase 2
Aurora, Colorado, United States and 16 other locations
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