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A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Charlotte, North Carolina, United States and 162 other locations
A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies
Phase 1, Phase 2
Charlotte, North Carolina, United States and 20 other locations
advanced solid tumors. Subjects with all histologic types of solid tumors are eligible for the escalation and dose-finding portion ...
Phase 1
Huntersville, North Carolina, United States of America and 10 other locations
study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 61 other locations
The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...
Phase 3
Charlotte, North Carolina, United States and 165 other locations
in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment ...
Phase 1
Charlotte, North Carolina, United States and 23 other locations
The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 49 other locations
with standard of care treatment (docetaxel) or another antibody cancer drug, pembrolizumab (with or without chemotherapy), for treatment of ...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 56 other locations
1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 6 other locations
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