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Find clinical trials for Endometrial Cancer in Charlotte, NC

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Related conditions:

Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
Lung Cancer

Endometrial Cancer trials near Charlotte, NC, USA:

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...

Enrolling
Endometrial Cancer
Endometrioid Endometrial Cancer
Drug: nab-sirolimus

Phase 2

Aadi Bioscience

Charlotte, North Carolina, United States and 8 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Paclitaxel
Drug: Carboplatin

Phase 3

Tesaro
Tesaro

Charlotte, North Carolina, United States and 162 other locations

A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies

Active, not recruiting
HER2-positive Endometrial Cancer
HER2-positive Colorectal Cancer
Drug: BDC-1001
Drug: Nivolumab

Phase 1, Phase 2

Bolt Biotherapeutics

Charlotte, North Carolina, United States and 20 other locations

advanced solid tumors. Subjects with all histologic types of solid tumors are eligible for the escalation and dose-finding portion ...

Active, not recruiting
Endometrial Cancer
Solid Tumor
Drug: TPST-1495 twice daily
Drug: TPST-1495 once daily or on intermittent schedule

Phase 1

Tempest Therapeutics

Huntersville, North Carolina, United States of America and 10 other locations

study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer...

Enrolling
Endometrial Cancer
Breast Cancer
Drug: AZD8205 and AZD2936 (Rilvegostomig)
Drug: AZD8205

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 61 other locations

The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...

Enrolling
Endometrial Cancer
Drug: Matching Placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Charlotte, North Carolina, United States and 165 other locations

in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment ...

Enrolling
Neoplasms
Drug: GSK4381562
Drug: GSK4428859A

Phase 1

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Charlotte, North Carolina, United States and 22 other locations

is to evaluate the safety of acasunlimab (also known as GEN1046) as monotherapy and in combination therapies in patients with malignant solid tumors...

Active, not recruiting
Endometrial Carcinoma
Non-small Cell Lung Cancer
Biological: Acasunlimab in combination with pembrolizumab (in a separate expansion cohort)
Biological: Acasunlimab in combination with docetaxel (in a single expansion cohort)

Phase 1, Phase 2

Genmab
Genmab

Charlotte, North Carolina, United States and 56 other locations

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...

Enrolling
Ovarian Neoplasms
Biliary Tract Neoplasms
Drug: Cetuximab
Drug: Cisplatin

Phase 1, Phase 2

Lilly
Lilly

Charlotte, North Carolina, United States and 49 other locations

1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors...

Enrolling
Endometrial Adenocarcinoma
Ovarian Cancer
Drug: APL-5125

Phase 1, Phase 2

Apollo Therapeutics

Huntersville, North Carolina, United States and 5 other locations

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