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The goal of this clinical trial is to assess if circulating tumor DNA can guide adjuvant selection in high-intermediate risk early-stage endometrial...
Charlotte, North Carolina, United States and 8 other locations
A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...
Phase 3
Charlotte, North Carolina, United States and 246 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Charlotte, North Carolina, United States and 168 other locations
to Part A (Phase 1a and Phase 1b) will include ovarian and endometrial cancers. Enrollment to Part B (Phase 1a and Phase 1b) will i...
Phase 1
Charlotte, North Carolina, United States and 11 other locations
antitumor activity of IMGN151 in adult participants with recurrent endometrial cancer; recurrent, high-grade serous epithelial ovar...
Phase 1
Charlotte, North Carolina, United States and 57 other locations
A phase 1a/1b, multicenter, open-label, dose escalation/expansion, multiple-dose study to evaluate the safety and activity of DR-0202 in patients wit...
Phase 1
Huntersville, North Carolina, United States and 9 other locations
This is a Phase 1/2, open-label, multicenter study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor ac...
Phase 1, Phase 2
Huntersville, North Carolina, United States of America and 14 other locations
in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment ...
Phase 1
Charlotte, North Carolina, United States and 25 other locations
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced ...
Phase 1, Phase 2
Huntersville, North Carolina, United States and 13 other locations
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