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Find clinical trials for Endometrial Cancer in Charlotte, NC

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Related conditions:

Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Ovarian Epithelial Carcinoma
Triple Negative Breast Cancer
Adenocarcinoma

Endometrial Cancer trials near Charlotte, NC, USA:

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...

Enrolling
Endometrial Cancer
Endometrioid Endometrial Cancer
Drug: nab-sirolimus

Phase 2

Aadi Bioscience

Charlotte, North Carolina, United States and 8 other locations

Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.

Active, not recruiting
Endometrial Cancer
Ovary Cancer
Drug: STRO-002

Phase 1

Sutro Biopharma

Charlotte, North Carolina, United States and 26 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Charlotte, North Carolina, United States and 162 other locations

A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies

Active, not recruiting
HER2-positive Endometrial Cancer
HER2-positive Colorectal Cancer
Drug: BDC-1001
Drug: Nivolumab

Phase 1, Phase 2

Bolt Biotherapeutics

Charlotte, North Carolina, United States and 25 other locations

However, the preferred tumor types for enrollment are colorectal cancer (CRC), non-small cell lung cancer (NSCLC), squamous cell ca ...

Active, not recruiting
Endometrial Cancer
Non Small Cell Lung Cancer
Drug: TPST-1495 once daily or on intermittent schedule
Drug: Pembrolizumab

Phase 1

Tempest Therapeutics

Huntersville, North Carolina, United States and 10 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI
Tempus AI

Charlotte, North Carolina, United States and 79 other locations

This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of GSK4381562...

Enrolling
Neoplasms
Drug: GSK4428859A
Drug: Dostarlimab

Phase 1

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Charlotte, North Carolina, United States and 22 other locations

study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer...

Enrolling
Endometrial Cancer
Breast Cancer
Drug: AZD8205 and AZD2936 (Rilvegostomig)
Drug: AZD8205

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 60 other locations

The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...

Enrolling
Endometrial Cancer
Drug: Matching Placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Charlotte, North Carolina, United States and 162 other locations

Status recently updated

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced...

Not yet enrolling
Enrolling
Endometrial Adenocarcinoma
Ovarian Cancer
Drug: APL-5125

Phase 1, Phase 2

Apollo Therapeutics

Huntersville, North Carolina, United States and 2 other locations

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