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A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.
Phase 1
Charlotte, North Carolina, United States and 26 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Charlotte, North Carolina, United States and 162 other locations
A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies
Phase 1, Phase 2
Charlotte, North Carolina, United States and 25 other locations
However, the preferred tumor types for enrollment are colorectal cancer (CRC), non-small cell lung cancer (NSCLC), squamous cell ca ...
Phase 1
Huntersville, North Carolina, United States and 10 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Charlotte, North Carolina, United States and 79 other locations
This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of GSK4381562...
Phase 1
Charlotte, North Carolina, United States and 22 other locations
study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 61 other locations
The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...
Phase 3
Charlotte, North Carolina, United States and 162 other locations
This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced...
Phase 1, Phase 2
Huntersville, North Carolina, United States and 2 other locations
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