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Find clinical trials for Endometrial Cancer in Charlotte, NC

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Related conditions:

Carcinoma
Cancer
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
Lung Cancer

Endometrial Cancer trials near Charlotte, NC, USA:

Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.

Enrolling
Endometrial Cancer
Ovary Cancer
Drug: STRO-002

Phase 1

Sutro Biopharma

Charlotte, North Carolina, United States and 26 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Charlotte, North Carolina, United States and 162 other locations

A first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignancies

Enrolling
HER2-positive Endometrial Cancer
HER2-positive Colorectal Cancer
Drug: BDC-1001
Drug: Nivolumab

Phase 1, Phase 2

Bolt Biotherapeutics

Charlotte, North Carolina, United States and 22 other locations

However, the preferred tumor types for enrollment are colorectal cancer (CRC), non-small cell lung cancer (NSCLC), squamous cell ca ...

Enrolling
Endometrial Cancer
Non Small Cell Lung Cancer
Drug: TPST-1495 once daily or on intermittent schedule
Drug: Pembrolizumab

Phase 1

Tempest Therapeutics

Huntersville, North Carolina, United States and 10 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI

Charlotte, North Carolina, United States and 79 other locations

This research study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours

Enrolling
Endometrial Cancer
Breast Cancer
Drug: AZD8205

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 52 other locations

This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of GSK4381562...

Enrolling
Neoplasms
Drug: GSK4428859A
Drug: Dostarlimab

Phase 1

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Charlotte, North Carolina, United States and 22 other locations

Amendment 5 is to obtain additional safety experience at the newly defined recommended Phase 2 dose of 500 mg every 4 weeks in patients with endometrial...

Active, not recruiting
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: retifanlimab

Phase 1

Incyte
Incyte

Huntersville, North Carolina, United States and 79 other locations

The purpose of the trial is to evaluate the safety of acasunlimab (also known as GEN1046) as monotherapy and in combination therapies in patients wit...

Active, not recruiting
Endometrial Carcinoma
Non-small Cell Lung Cancer
Biological: Acasunlimab in combination with pembrolizumab (in a separate expansion cohort)
Biological: Acasunlimab in combination with docetaxel (in a single expansion cohort)

Phase 1, Phase 2

Genmab
Genmab

Charlotte, North Carolina, United States and 56 other locations

This is an open-label, dose-escalation and dose-expansion study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy...

Enrolling
Solid Tumors
Drug: INCB0123667

Phase 1

Incyte
Incyte

Huntersville, North Carolina, United States and 33 other locations

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