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(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Cleveland, Ohio, United States and 202 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Cleveland, Ohio, United States and 152 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Cleveland, Ohio, United States and 168 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Cleveland, Ohio, United States and 66 other locations
pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients with advanced solid tumors...
Phase 1, Phase 2
Cleveland, Ohio, United States and 8 other locations
first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...
Phase 1
Cleveland, Ohio, United States and 12 other locations
The purpose of this trial is to measure the following in participants with solid tumors who receive GEN1047:* The side effects seen with GEN...
Phase 1, Phase 2
Cleveland, Ohio, United States and 35 other locations
dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial...
Phase 1, Phase 2
Cleveland, Ohio, United States and 109 other locations
objective response rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by investigator in participants pro ...
Phase 2
Cleveland, Ohio, United States and 44 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Cleveland, Ohio, United States and 123 other locations
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