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Find clinical trials for Endometrial Cancer in Cleveland, OH

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Related conditions:

Ovarian Cancer
Non-Small-Cell Lung Carcinoma
Breast Cancer
Colorectal Cancer
Cancer
Stomach Cancer
Uterine Cervical Cancer

Endometrial Cancer trials near Cleveland, OH, USA:

Signatera Assessment in Early-Stage Endometrial Cancer (SIGNAL-EMC 101)

The goal of this clinical trial is to assess if circulating tumor DNA can guide adjuvant selection in high-intermediate risk early-stage endometrial...

Begins enrollment this month
Endometrial Cancer
Device: Signatera Genome ultra-sensitive ctDNA blood test
Natera
Natera

Cleveland, Ohio, United States and 11 other locations

This is a Phase III, 2-arm, randomized, open label, multicenter, global study assessing the efficacy and safety of puxitatug samrotecan compared to p...

Enrolling
Endometrial Cancer
Malignant Solid Tumour
Drug: Puxitatug Samrotecan
Drug: Paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 318 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Drug: Carboplatin
Biological: durvalumab

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 201 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Paclitaxel
Drug: Carboplatin

Phase 3

Tesaro
Tesaro

Cleveland, Ohio, United States and 168 other locations

The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...

Active, not recruiting
Endometrial Cancer
Drug: Paclitaxel
Drug: Sacituzumab govitecan-hziy

Phase 3

Gilead Sciences
Gilead Sciences

Cleveland, Ohio, United States and 188 other locations

to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...

Enrolling
Endometrial Adenocarcinoma
Drug: ACR-368
Diagnostic Test: OncoSignature

Phase 2

Acrivon Therapeutics

Cleveland, Ohio, United States and 89 other locations

HWK-007-101 is a multicenter, open-label, first-in-human (FIH) Phase 1 study evaluating HWK-007, a protein tyrosine kinase 7 (PTK7)-targeted antibody...

Enrolling
Endometrial Cancer
Ovarian Cancer Metastatic Recurrent
Drug: HWK-007

Phase 1

Whitehawk Therapeutics, Inc.

Cleveland, Ohio, United States and 11 other locations

This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated d...

Enrolling
Endometrial Cancer
Primary Peritoneal Cancer
Drug: Sacituzumab Govitecan-hziy
Drug: Ribociclib

Phase 1, Phase 2

Avenzo Therapeutics

Cleveland, Ohio, United States and 12 other locations

first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...

Enrolling
Endometrial Cancer
Ovarian Cancer
Drug: TORL-1-23

Phase 1

TORL Biotherapeutics

Cleveland, Ohio, United States and 13 other locations

-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...

Active, not recruiting
Castration-resistant Prostate Cancer
Lower Esophageal Cancer
Drug: cabozantinib
Drug: atezolizumab

Phase 1

Exelixis
Exelixis

Cleveland, Ohio, United States and 123 other locations

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