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(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Cleveland, Ohio, United States and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Cleveland, Ohio, United States and 168 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Cleveland, Ohio, United States and 66 other locations
first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...
Phase 1
Cleveland, Ohio, United States and 4 other locations
The purpose of this trial is to measure the following in participants with solid tumors who receive GEN1047:* The side effects seen with GEN...
Phase 1, Phase 2
Cleveland, Ohio, United States and 35 other locations
objective response rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by investigator in participants pro ...
Phase 2
Cleveland, Ohio, United States and 44 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Cleveland, Ohio, United States and 123 other locations
tumors....
Phase 1
Cleveland, Ohio, United States and 7 other locations
and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors....
Phase 1
Cleveland, Ohio, United States and 94 other locations
multiple dose levels of PC14586 (INN: rezatapopt) alone (monotherapy) and in combination with pembrolizumab in participants with advanced solid tumors...
Phase 1, Phase 2
Cleveland, Ohio, United States and 65 other locations
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