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The goal of this clinical trial is to assess if circulating tumor DNA can guide adjuvant selection in high-intermediate risk early-stage endometrial...
Cleveland, Ohio, United States and 11 other locations
This is a Phase III, 2-arm, randomized, open label, multicenter, global study assessing the efficacy and safety of puxitatug samrotecan compared to p...
Phase 3
Cleveland, Ohio, United States and 318 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Cleveland, Ohio, United States and 201 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Cleveland, Ohio, United States and 168 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Cleveland, Ohio, United States and 188 other locations
to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...
Phase 2
Cleveland, Ohio, United States and 89 other locations
HWK-007-101 is a multicenter, open-label, first-in-human (FIH) Phase 1 study evaluating HWK-007, a protein tyrosine kinase 7 (PTK7)-targeted antibody...
Phase 1
Cleveland, Ohio, United States and 11 other locations
This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated d...
Phase 1, Phase 2
Cleveland, Ohio, United States and 12 other locations
first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...
Phase 1
Cleveland, Ohio, United States and 13 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1
Cleveland, Ohio, United States and 123 other locations
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