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(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Cleveland, Ohio, United States and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Cleveland, Ohio, United States and 162 other locations
compared to Tamoxifen and Medroxyprogesterone acetate in treating endometrial cancer and to determine the types and severity of sid...
Phase 2
Cleveland, Ohio, United States and 25 other locations
This is a Phase 1 dose-escalation study of PRT3645, a Cyclin-dependent Kinase 4/6 (CDK4/6) inhibitor, in patients with advanced or metastatic solid t...
Phase 1
Cleveland, Ohio, United States and 12 other locations
This study, ELU- FRα-1, is focused on adult subjects who have advanced, recurrent or refractory folate receptor alpha (FRα) overexpressing tumors con...
Phase 1, Phase 2
Cleveland, Ohio, United States and 17 other locations
This is a Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary clinical activ...
Phase 1
Cleveland, Ohio, United States and 10 other locations
The goal of this clinical trial is to evaluate the safety of TOS-358 in adults with select solid tumors who meet study enrollment criteria. The main...
Phase 1
Cleveland, Ohio, United States and 11 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Cleveland, Ohio, United States and 67 other locations
first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...
Phase 1
Cleveland, Ohio, United States and 3 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Cleveland, Ohio, United States and 79 other locations
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