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Find clinical trials for Endometrial Cancer in Durham, NC

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Related conditions:

Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
Lung Cancer

Endometrial Cancer trials near Durham, NC, USA:

ONC201 in Recurrent or Metastatic Type II Endometrial Cancer Endometrial Cancer

This is a a Simon's two-stage, non-randomized, open label, 2-arm Phase II trial of ONC201 in women with metastatic or recurrent Type II endometrial...

Active, not recruiting
Endometrial Cancer Recurrent
Drug: ONC201

Phase 2

Chimerix
Chimerix

Chapel Hill, North Carolina, United States and 2 other locations

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...

Enrolling
Endometrial Cancer
Drug: Talazoparib
Drug: Bevacizumab

Phase 1, Phase 2

Alliance Foundation Trials

Durham, North Carolina, United States and 19 other locations

Endometrial cancer (EC) is the fourth most common cancer in United States women, and alarmingly, the frequency and mortali...

Enrolling
Endometrial Cancer
Metastasis
Drug: ONC201
Drug: Atezolizumab

Phase 1

UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, United States of America

This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial...

Enrolling
Endometrial Cancer
Drug: INCAGN02390
Drug: pemigatinib

Phase 2

Incyte
Incyte

Chapel Hill, North Carolina, United States of America and 66 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Durham, North Carolina, United States and 162 other locations

drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer...

Active, not recruiting
Endometrial Cancer
Breast Cancer
Drug: Trastuzumab
Drug: Everolimus

Phase 1

Lilly
Lilly

Durham, North Carolina, United States and 75 other locations

choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to rece...

Active, not recruiting
Endometrial Neoplasms
Drug: Pembrolizumab
Drug: Doxorubicin

Phase 3

Eisai
Eisai

Durham, North Carolina, United States and 168 other locations

antigen (HLA) and MAGE-A4 tumor antigen. Tumor indications include endometrial, esophageal, esophagogastric junction (EGJ), gastric, head an....

Enrolling
Endometrial Cancer
Esophageal Cancer
Genetic: Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks

Phase 1

Adaptimmune

Durham, North Carolina, United States and 21 other locations

This study, ELU- FRα-1, is focused on adult subjects who have advanced, recurrent or refractory folate receptor alpha (FRα) overexpressing tumors con...

Enrolling
Ovarian Cancer Stage
Fallopian Tube Cancer
Drug: ELU001

Phase 1, Phase 2

Elucida Oncology

Durham, North Carolina, United States and 17 other locations

Phase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.

Active, not recruiting
Lung Cancer, Non-Small-Cell
HER2-positive Breast Cancer
Biological: CT-0508
Biological: Pembrolizumab

Phase 1

Carisma Therapeutics

Chapel Hill, North Carolina, United States and 6 other locations

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