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Find clinical trials for Endometrial Cancer in Indianapolis, IN

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Related conditions:

Carcinoma
Cancer
Ovarian Cancer
Breast Cancer
Ovarian Epithelial Carcinoma
Triple Negative Breast Cancer
Lung Cancer

Endometrial Cancer trials near Indianapolis, IN, USA:

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer (DUO-E)

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Biological: durvalumab
Drug: olaparib

Phase 3

AstraZeneca
AstraZeneca

Indianapolis, Indiana, United States and 202 other locations

for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Indianapolis, Indiana, United States and 77 other locations

This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have ...

Enrolling
Endometrial Cancer
Drug: Navtemadlin Placebo
Drug: Navtemadlin

Phase 2, Phase 3

Kartos Therapeutics

Indianapolis, Indiana, United States and 82 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Indianapolis, Indiana, United States and 162 other locations

drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer...

Active, not recruiting
Endometrial Cancer
Breast Cancer
Drug: Trastuzumab
Drug: Everolimus

Phase 1

Lilly
Lilly

Indianapolis, Indiana, United States and 75 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI
Tempus AI

Indianapolis, Indiana, United States and 79 other locations

TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Com...

Enrolling
Endometrial Cancer
Gastric Cancer
Drug: Carboplatin
Drug: Leucovorin LV

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 92 other locations

The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, wit...

Active, not recruiting
Endometrial Neoplasms
Drug: Placebo for pembrolizumab
Drug: Cisplatin (as radiosensitizer)

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Indianapolis, Indiana, United States and 230 other locations

consist of Part 1 which includes 7 cohorts of: urothelial bladder cancer, biliary tract cancer, cervical cancer, endometrial...

Enrolling
Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 113 other locations

The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...

Enrolling
Endometrial Cancer
Drug: Matching Placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Indianapolis, Indiana, United States and 162 other locations

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