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This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...
Phase 1, Phase 2
Westwood, Kansas, United States and 20 other locations
This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial...
Phase 2
Kansas City, Missouri, United States and 65 other locations
for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...
Phase 3
Kansas City, Missouri, United States and 77 other locations
This study will test the safety, including side effects, and determine the characteristics of a drug called PRO1184 in participants with solid tumors...
Phase 1, Phase 2
Westwood, Kansas, United States and 31 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Kansas City, Missouri, United States and 67 other locations
dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial...
Phase 1, Phase 2
Kansas City, Missouri, United States of America and 59 other locations
TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Com...
Phase 2
Kansas City, Kansas, United States and 92 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Kansas City, Missouri, United States and 123 other locations
BBI-355 is an oral, potent, selective checkpoint kinase 1 (or CHK1) small molecule inhibitor in development as an ecDNA (extrachromosomal DNA) direct...
Phase 1
Fairway, Kansas, United States and 14 other locations
The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial...
Phase 3
Kansas City, Missouri, United States and 166 other locations
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