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This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...
Phase 1, Phase 2
Westwood, Kansas, United States and 19 other locations
This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial...
Phase 2
Kansas City, Missouri, United States and 66 other locations
for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...
Phase 3
Kansas City, Missouri, United States and 76 other locations
in participants with solid tumors.Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be remov...
Phase 1, Phase 2
Westwood, Kansas, United States and 21 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Kansas City, Missouri, United States and 67 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Saint Joseph, Missouri, United States and 79 other locations
TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Com...
Phase 2
Kansas City, Kansas, United States and 92 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Kansas City, Missouri, United States and 123 other locations
The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combina...
Phase 1
Kansas City, Missouri, United States of America and 47 other locations
This is a Phase 1A/B study consisting of four parts.Part A (completed) is a non-randomised, open-label, sequential evaluation of the safety, pharmaco...
Phase 1
Fairway, Kansas, United States and 10 other locations
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