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This is a a Simon's two-stage, non-randomized, open label, 2-arm Phase II trial of ONC201 in women with metastatic or recurrent Type II endometrial...
Phase 2
Philadelphia, Pennsylvania, United States of America and 2 other locations
letrozole in advanced stage, persistent or recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until eit...
Phase 2
Willow Grove, Pennsylvania, United States and 28 other locations
Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor...
Phase 1
Philadelphia, Pennsylvania, United States and 20 other locations
Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...
Phase 3
Philadelphia, Pennsylvania, United States and 223 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Camden, New Jersey, United States and 202 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Horsham, Pennsylvania, United States and 35 other locations
This phase II trial studies the effect of onapristone and anastrozole in treating patients with hormone receptor positive endometrial cancer...
Phase 2
Philadelphia, Pennsylvania, United States and 1 other location
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Philadelphia, Pennsylvania, United States and 168 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Philadelphia, Pennsylvania, United States and 16 other locations
in patients with ROR1+ relapsed or refractory triple negative breast cancer (TNBC), non-small cell lung cancer (NSCLC), platinum-re ...
Phase 1
Philadelphia, Pennsylvania, United States and 17 other locations
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