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Find clinical trials for Endometrial Cancer in Philadelphia, PA

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Related conditions:

Carcinoma
Cancer
Ovarian Cancer
Breast Cancer
Ovarian Epithelial Carcinoma
Triple Negative Breast Cancer
Adenocarcinoma

Endometrial Cancer trials near Philadelphia, PA, USA:

ONC201 in Recurrent or Metastatic Type II Endometrial Cancer Endometrial Cancer

This is a a Simon's two-stage, non-randomized, open label, 2-arm Phase II trial of ONC201 in women with metastatic or recurrent Type II endometrial...

Active, not recruiting
Endometrial Cancer Recurrent
Drug: ONC201

Phase 2

Chimerix
Chimerix

Philadelphia, Pennsylvania, United States of America and 2 other locations

letrozole in advanced stage, persistent or recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until eit...

Active, not recruiting
Endometrial Cancer
Drug: Abemaciclib
Drug: Letrozole

Phase 2

Gynecologic Oncology Group (GOG)

Willow Grove, Pennsylvania, United States and 28 other locations

Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor...

Enrolling
Endometrial Cancer
Lung Cancer
Drug: Docetaxel
Drug: Carboplatin

Phase 1

Inspirna

Philadelphia, Pennsylvania, United States and 20 other locations

Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.

Active, not recruiting
Endometrial Cancer
Ovary Cancer
Drug: STRO-002

Phase 1

Sutro Biopharma

Philadelphia, Pennsylvania, United States and 26 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Drug: Carboplatin
Biological: durvalumab

Phase 3

AstraZeneca
AstraZeneca

Camden, New Jersey, United States and 202 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Philadelphia, Pennsylvania, United States and 162 other locations

This phase II trial studies the effect of onapristone and anastrozole in treating patients with hormone receptor positive endometrial cancer...

Active, not recruiting
Refractory Endometrial Clear Cell Adenocarcinoma
Refractory Endometrial Undifferentiated Carcinoma
Other: Questionnaire Administration
Diagnostic Test: Progesterone Receptor Positive ( PGR Positive; PR Positive)

Phase 2

Thomas Jefferson University
Thomas Jefferson University

Philadelphia, Pennsylvania, United States and 1 other location

compared to Tamoxifen and Medroxyprogesterone acetate in treating endometrial cancer and to determine the types and severity of sid...

Active, not recruiting
Advanced, Persistent, or Recurrent Endometrial Cancer
Drug: Medroxyprogesterone Acetate
Drug: Tamoxifen

Phase 2

GOG Foundation

Philadelphia, Pennsylvania, United States and 25 other locations

This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...

Enrolling
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Endometrial Cancer
Biological: vudalimab

Phase 2

Xencor
Xencor

Philadelphia, Pennsylvania, United States and 11 other locations

antigen (HLA) and MAGE-A4 tumor antigen. Tumor indications include endometrial, esophageal, esophagogastric junction (EGJ), gastric, head an....

Enrolling
Endometrial Cancer
Esophageal Cancer
Genetic: Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks

Phase 1

Adaptimmune

Philadelphia, Pennsylvania, United States and 21 other locations

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