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This is a a Simon's two-stage, non-randomized, open label, 2-arm Phase II trial of ONC201 in women with metastatic or recurrent Type II endometrial...
Phase 2
Philadelphia, Pennsylvania, United States of America and 2 other locations
letrozole in advanced stage, persistent or recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until eit...
Phase 2
Willow Grove, Pennsylvania, United States and 28 other locations
Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.
Phase 1
Philadelphia, Pennsylvania, United States and 26 other locations
Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor...
Phase 1
Philadelphia, Pennsylvania, United States and 20 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Camden, New Jersey, United States and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Philadelphia, Pennsylvania, United States and 162 other locations
This phase II trial studies the effect of onapristone and anastrozole in treating patients with hormone receptor positive endometrial cancer...
Phase 2
Philadelphia, Pennsylvania, United States and 1 other location
compared to Tamoxifen and Medroxyprogesterone acetate in treating endometrial cancer and to determine the types and severity of sid...
Phase 2
Philadelphia, Pennsylvania, United States and 25 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Philadelphia, Pennsylvania, United States and 11 other locations
This is a Phase 1 dose-escalation study of PRT3645, a Cyclin-dependent Kinase 4/6 (CDK4/6) inhibitor, in patients with advanced or metastatic solid t...
Phase 1
Philadelphia, Pennsylvania, United States and 12 other locations
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