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Find clinical trials for Endometrial Cancer in Pittsburgh, PA

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Related conditions:

Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
Lung Cancer

Endometrial Cancer trials near Pittsburgh, PA, USA:

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer (EndoMAP)

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...

Enrolling
Endometrial Cancer
Drug: Talazoparib
Drug: Bevacizumab

Phase 1, Phase 2

Alliance Foundation Trials

Pittsburgh, Pennsylvania, United States and 20 other locations

study is designed to evaluate the efficacy, safety, and pharmacokinetics of giredestrant monotherapy in participants with Grade 1 endometrioid endometrial...

Enrolling
Endometrial Cancer
Drug: Giredestrant

Phase 2

Roche
Roche

Pittsburgh, Pennsylvania, United States and 20 other locations

Locations recently updated

Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...

Enrolling
Endometrial Cancer
Drug: Paclitaxel
Drug: Doxorubicin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 200 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Drug: Carboplatin
Biological: durvalumab

Phase 3

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 202 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Paclitaxel
Drug: Carboplatin

Phase 3

Tesaro
Tesaro

Pittsburgh, Pennsylvania, United States and 162 other locations

in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...

Enrolling
Endometrial Adenocarcinoma
Platinum-resistant Ovarian Cancer
Drug: ACR-368
Diagnostic Test: OncoSignature

Phase 1, Phase 2

Acrivon Therapeutics

Pittsburgh, Pennsylvania, United States and 67 other locations

This interventional study will evaluate the efficacy and safety of ART0380 as monotherapy in patients whose tumors have a biology to predict...

Enrolling
Metastatic Cancer
Recurrent Endometrial Cancer
Drug: ART0380

Phase 2

Artios Pharma

Pittsburgh, Pennsylvania, United States and 14 other locations

advanced solid tumors. Subjects with all histologic types of solid tumors are eligible for the escalation and dose-finding portion ...

Active, not recruiting
Endometrial Cancer
Solid Tumor
Drug: TPST-1495 twice daily
Drug: TPST-1495 once daily or on intermittent schedule

Phase 1

Tempest Therapeutics

Pittsburgh, Pennsylvania, United States and 10 other locations

The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, wit...

Active, not recruiting
Endometrial Neoplasms
Drug: Placebo for pembrolizumab
Drug: Cisplatin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 230 other locations

objective response rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by investigator in participants pro ...

Enrolling
Endometrial Cancer
Solid Tumor
Drug: lenvatinib
Biological: pembrolizumab

Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 40 other locations

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