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This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 19 other locations
study is designed to evaluate the efficacy, safety, and pharmacokinetics of giredestrant monotherapy in participants with Grade 1 endometrioid endometrial...
Phase 2
Pittsburgh, Pennsylvania, United States and 18 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Pittsburgh, Pennsylvania, United States and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Pittsburgh, Pennsylvania, United States and 162 other locations
compared to Tamoxifen and Medroxyprogesterone acetate in treating endometrial cancer and to determine the types and severity of sid...
Phase 2
Pittsburgh, Pennsylvania, United States and 25 other locations
This is a phase 1/2 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor ac...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 8 other locations
This interventional study will evaluate the efficacy and safety of ART0380 as monotherapy in patients whose tumors have a biology to predict for sens...
Phase 2
Pittsburgh, Pennsylvania, United States and 8 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 67 other locations
However, the preferred tumor types for enrollment are colorectal cancer (CRC), non-small cell lung cancer (NSCLC), squamous cell ca ...
Phase 1
Pittsburgh, Pennsylvania, United States and 10 other locations
-small-cell lung cancer (NSCLC), triple negative breast cancer (TNBC), ovarian cancer (OC), endometrial cancer...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 123 other locations
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