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The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial...
Phase 2
Pittsburgh, Pennsylvania, United States and 2 other locations
This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 20 other locations
study is designed to evaluate the efficacy, safety, and pharmacokinetics of giredestrant monotherapy in participants with Grade 1 endometrioid endometrial...
Phase 2
Pittsburgh, Pennsylvania, United States and 15 other locations
Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...
Phase 3
Pittsburgh, Pennsylvania, United States and 223 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Pittsburgh, Pennsylvania, United States and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Pittsburgh, Pennsylvania, United States and 168 other locations
in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSigna...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 66 other locations
This interventional study will evaluate the efficacy and safety of ART0380 as monotherapy in patients whose tumors have a biology to predict...
Phase 2
Pittsburgh, Pennsylvania, United States and 14 other locations
T-cell therapy product genetically engineered to express an HLA-C\*08:02-restricted T cell receptor (TCR), targeting KRAS G12D mutant solid tumors...
Phase 1
Pittsburgh, Pennsylvania, United States and 11 other locations
advanced solid tumors. Subjects with all histologic types of solid tumors are eligible for the escalation and dose-finding portion ...
Phase 1
Pittsburgh, Pennsylvania, United States and 10 other locations
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