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The RAINBO umbrella program consists of four clinical trials investigating new adjuvant therapies in endometrial cancer patients. E ...
Phase 2, Phase 3
Toronto, Canada and 13 other locations
This is a phase 2 study of investigational drug niraparib and TSR-042 in patients with advanced/recurrent endometrial cancer. The p ...
Phase 2
Toronto, Ontario, Canada and 6 other locations
for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...
Phase 3
Toronto, Ontario, Canada and 76 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Toronto, Ontario, Canada and 202 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Toronto, Ontario, Canada and 162 other locations
choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to rece...
Phase 3
Toronto, Ontario, Canada and 168 other locations
antigen (HLA) and MAGE-A4 tumor antigen. Tumor indications include endometrial, esophageal, esophagogastric junction (EGJ), gastric, head an....
Phase 1
Toronto, Ontario, Canada and 21 other locations
to other places in the body, it is called advanced or metastatic cancer. Participants in this study must have head and neck squamous cell ca ...
Phase 2
Toronto, Ontario, Canada and 26 other locations
TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Com...
Phase 2
Toronto, Ontario, Canada and 92 other locations
per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by investigator in participants proficient in mismatch repair (pMMR) endometrial...
Phase 2
Toronto, Ontario, Canada and 35 other locations
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