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Find clinical trials for Endometrial Cancer in Toronto, ON

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Cancer
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Breast Cancer
Triple Negative Breast Cancer
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Endometrial Cancer trials near Toronto, ON, CAN:

Refining Adjuvant Treatment in Endometrial Cancer Based on Molecular Features (RAINBO)

The RAINBO umbrella program consists of four clinical trials investigating new adjuvant therapies in endometrial cancer patients. E ...

Enrolling
Endometrial Cancer
Radiation: Vaginal brachytherapy
Drug: Megestrol Acetate

Phase 2, Phase 3

Leiden University Medical Center (LUMC)

Toronto, Canada and 13 other locations

This is a phase 2 study of investigational drug niraparib and TSR-042 in patients with advanced/recurrent endometrial cancer. The p ...

Active, not recruiting
Endometrial Cancer
Drug: TSR-042
Drug: Niraparib

Phase 2

University Health Network, Toronto
University Health Network, Toronto

Toronto, Ontario, Canada and 6 other locations

Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...

Enrolling
Endometrial Cancer
Drug: Paclitaxel
Drug: Doxorubicin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Mississauga, Ontario, Canada and 223 other locations

for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Toronto, Ontario, Canada and 77 other locations

study to evaluate the efficacy and safety of dostarlimab versus carboplatin-paclitaxel in patients with MMR deficient relapse or advanced endometrial...

Enrolling
Endometrial Cancer
Drug: Carboplatin-Paclitaxel
Drug: Dostarlimab

Phase 3

ARCAGY/ GINECO GROUP

Toronto, Canada and 94 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Drug: Carboplatin
Biological: durvalumab

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 202 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Paclitaxel
Drug: Carboplatin

Phase 3

Tesaro
Tesaro

Toronto, Ontario, Canada and 168 other locations

choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to rece...

Active, not recruiting
Endometrial Neoplasms
Drug: Doxorubicin
Drug: Paclitaxel

Phase 3

Eisai
Eisai

Toronto, Ontario, Canada and 168 other locations

who have the appropriate human leukocyte antigen (HLA) and MAGE-A4 tumor antigen. Tumor indications include endometrial, e....

Enrolling
Endometrial Cancer
Esophageal Cancer
Genetic: Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks

Phase 1

Adaptimmune

Toronto, Ontario, Canada and 21 other locations

durvalumab (MEDI4736) in patients with relapsed gynaecological cancers to assess the response in groups of patients selected based on their ...

Enrolling
Gynaecological Cancers
Drug: Durvalumab
Drug: Ceralasertib

Phase 2

Institute of Cancer Research, United Kingdom

Toronto, Ontario, Canada and 8 other locations

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