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Find clinical trials for Endometrial Cancer in Toronto, ON

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Related conditions:

Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
Lung Cancer

Endometrial Cancer trials near Toronto, ON, CAN:

Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features (RAINBO)

The RAINBO umbrella program consists of four clinical trials investigating new adjuvant therapies in endometrial cancer patients. E ...

Enrolling
Endometrial Cancer
Drug: Megestrol Acetate
Drug: Durvalumab

Phase 2, Phase 3

Leiden University Medical Center (LUMC)

Toronto, Canada and 13 other locations

This is a phase 2 study of investigational drug niraparib and TSR-042 in patients with advanced/recurrent endometrial cancer. The p ...

Active, not recruiting
Endometrial Cancer
Drug: TSR-042
Drug: Niraparib

Phase 2

University Health Network, Toronto
University Health Network, Toronto

Toronto, Ontario, Canada and 6 other locations

for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recu...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Phase 3

Karyopharm Therapeutics
Karyopharm Therapeutics

Toronto, Ontario, Canada and 76 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Biological: durvalumab
Drug: olaparib

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 202 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

Tesaro
Tesaro

Toronto, Ontario, Canada and 162 other locations

choice (doxorubicin or paclitaxel) for the treatment of advanced endometrial cancer. Participants will be randomly assigned to rece...

Active, not recruiting
Endometrial Neoplasms
Drug: Pembrolizumab
Drug: Doxorubicin

Phase 3

Eisai
Eisai

Toronto, Ontario, Canada and 168 other locations

antigen (HLA) and MAGE-A4 tumor antigen. Tumor indications include endometrial, esophageal, esophagogastric junction (EGJ), gastric, head an....

Enrolling
Endometrial Cancer
Esophageal Cancer
Genetic: Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks

Phase 1

Adaptimmune

Toronto, Ontario, Canada and 21 other locations

to other places in the body, it is called advanced or metastatic cancer. Participants in this study must have head and neck squamous cell ca ...

Enrolling
Endometrial Neoplasms
Ovarian Neoplasms
Drug: disitamab vedotin

Phase 2

Seagen
Seagen

Toronto, Ontario, Canada and 26 other locations

TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Com...

Enrolling
Endometrial Cancer
Gastric Cancer
Drug: Carboplatin
Drug: Leucovorin LV

Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 92 other locations

per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by investigator in participants proficient in mismatch repair (pMMR) endometrial...

Enrolling
Endometrial Cancer
Solid Tumor
Drug: lenvatinib
Biological: pembrolizumab

Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Toronto, Ontario, Canada and 35 other locations

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