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Find clinical trials for Glioblastoma (GBM) in Ann Arbor, MI

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Ann Arbor, MI, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-5401

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Detroit, Michigan, United States and 20 other locations

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Ann Arbor, Michigan, United States and 85 other locations

Locations recently updated

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Biological: ADI-PEG 20
Drug: VT1021

Phase 2, Phase 3

Global Coalition for Adaptive Research

Detroit, Michigan, United States and 60 other locations

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting
Brain Neoplasms
Other: Nivolumab Placebo
Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Detroit, Michigan, United States and 122 other locations

OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treate...

Active, not recruiting
Brain Glioblastoma
Recurrent Malignant Glioma
Drug: Temozolomide (TMZ)
Drug: OKN-007

Phase 2

Oblato

Detroit, Michigan, United States and 12 other locations

The purpose of this study is to assess progression-free survival (PFS) and overall survival (OS) in newly diagnosed Glioblastoma (GBM...

Enrolling
Glioblastoma
Drug: SOC: Temozolomide
Combination Product: Placebo

Phase 2

Imvax

Detroit, Michigan, United States and 22 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Ann Arbor, Michigan, United States and 132 other locations

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: Eflornithine (Dose Level 2)

Phase 1

Orbus Therapeutics

Detroit, Michigan, United States and 7 other locations

To evaluate the safety and tolerability of escalating doses of ERAS-801 in study participants with recurrent glioblastoma multiforme (GBM...

Active, not recruiting
Glioblastoma Multiforme
Drug: ERAS-801

Phase 1

Erasca

Detroit, Michigan, United States and 7 other locations

alone versus bevacizumab in patients diagnosed with recurrent glioblastoma (a type of brain cancer, also known as GBM), and to eval...

Active, not recruiting
Recurrent Glioblastoma
Biological: Nivolumab
Biological: Ipilimumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Detroit, Michigan, United States and 112 other locations

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