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Find clinical trials for Glioblastoma (GBM) in Ann Arbor, MI

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Related conditions:

Glioblastoma
Recurrence
Glioma
Brain Cancer
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Ann Arbor, MI, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-5401

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Detroit, Michigan, United States and 20 other locations

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Ann Arbor, Michigan, United States and 85 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Biological: ADI-PEG 20
Drug: VT1021

Phase 2, Phase 3

Global Coalition for Adaptive Research

Detroit, Michigan, United States and 60 other locations

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting
Brain Neoplasms
Other: Nivolumab Placebo
Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Detroit, Michigan, United States and 122 other locations

OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treate...

Active, not recruiting
Brain Glioblastoma
Recurrent Malignant Glioma
Drug: Temozolomide (TMZ)
Drug: OKN-007

Phase 2

Oblato

Detroit, Michigan, United States and 12 other locations

The purpose of this study is to assess progression-free survival (PFS) and overall survival (OS) in newly diagnosed Glioblastoma (GBM...

Enrolling
Glioblastoma
Drug: SOC: Temozolomide
Combination Product: Placebo

Phase 2

Imvax

Detroit, Michigan, United States and 22 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Ann Arbor, Michigan, United States and 132 other locations

Locations recently updated

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: Eflornithine (Dose Level 2)

Phase 1

Orbus Therapeutics

Detroit, Michigan, United States and 7 other locations

To evaluate the safety and tolerability of escalating doses of ERAS-801 in study participants with recurrent glioblastoma multiforme (GBM...

Active, not recruiting
Glioblastoma Multiforme
Drug: ERAS-801

Phase 1

Erasca

Detroit, Michigan, United States and 7 other locations

alone versus bevacizumab in patients diagnosed with recurrent glioblastoma (a type of brain cancer, also known as GBM), and to eval...

Active, not recruiting
Recurrent Glioblastoma
Biological: Nivolumab
Biological: Ipilimumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Detroit, Michigan, United States and 112 other locations

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