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The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...
Phase 3
Aurora, Colorado, United States and 85 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Aurora, Colorado, United States and 60 other locations
OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treate...
Phase 2
Englewood, Colorado, United States and 12 other locations
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...
Aurora, Colorado, United States and 132 other locations
(TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic can...
Phase 2
Aurora, Colorado, United States and 87 other locations
This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy o...
Phase 1, Phase 2
Denver, Colorado, United States and 11 other locations
Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do cli...
Phase 2
Aurora, Colorado, United States and 33 other locations
This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...
Phase 2
Englewood, Colorado, United States and 55 other locations
alone versus bevacizumab in patients diagnosed with recurrent glioblastoma (a type of brain cancer, also known as GBM), and to eval...
Phase 3
Aurora, Colorado, United States and 112 other locations
receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma multiforme (GBM...
Phase 1, Phase 2
Denver, Colorado, United States and 25 other locations
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