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FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...
Phase 1
Baltimore, Maryland, United States and 8 other locations
the feasibility of adding MRSI to the evaluation of newly-diagnosed GBM patients treated with standard RT/TMZ and determine whether magnetic...
Phase 2
Baltimore, Maryland, United States and 1 other location
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Baltimore, Maryland, United States and 80 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Baltimore, Maryland, United States and 47 other locations
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
Baltimore, Maryland, United States and 28 other locations
This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...
Phase 1, Phase 2
Fairfax, Virginia, United States and 19 other locations
This phase I trial studies the side effects of stereotactic radiosurgery with MBG453 and spartalizumab in treating patients with recurrent glioblastoma...
Phase 1
Baltimore, Maryland, United States and 1 other location
This clinical trial is testing the safety and efficacy of NanO2TM administered via intravenous infusion in combination with standard radiation and ch...
Phase 2
Fairfax, Virginia, United States and 11 other locations
via ICV in participants with recurrent or progressive IDH-wildtype glioblastoma (WHO 2021 CNS Grade 4), who have previously received standar...
Phase 2
Baltimore, Maryland, United States and 3 other locations
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