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efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...
Phase 1, Phase 2
Boston, Massachusetts, United States and 20 other locations
trial will evaluate the safety, tolerability, immunogenicity, and preliminary efficacy of 8 mg ITI-1001 in participants with newly diagnosed glioblastoma...
Phase 1
Boston, Massachusetts, United States
A Phase 1b/2, Multicenter, Open-Label Study of ACP-196 in Subjects with Recurrent Glioblastoma Multiforme (GBM)...
Phase 1, Phase 2
Boston, Massachusetts, United States and 6 other locations
In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local con...
Phase 4
Providence, Rhode Island, United States and 13 other locations
Part 1 is an open-label, single-arm, dose escalation study of MN-166 (ibudilast) and temozolomide (TMZ) combination treatment. Evaluate safety and to...
Phase 1, Phase 2
Boston, Massachusetts, United States
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Boston, Massachusetts, United States and 61 other locations
with ipilimumab and surgery when used in the treatment of recurrent glioblastoma.The names of the study drugs involved in this study are:* N...
Phase 1
Boston, Massachusetts, United States and 3 other locations
This research study is studying troriluzole as a possible treatment for recurrent glioblastoma.The name of the study drug involved in this r...
Early Phase 1
Boston, Massachusetts, United States and 2 other locations
as a monotherapy in participants with newly diagnosed or recurrent epidermal growth factor receptor variant III (EGFRvIII)-positive glioblastoma...
Phase 1
Boston, Massachusetts, United States and 10 other locations
OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treate...
Phase 2
Providence, Rhode Island, United States and 12 other locations
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