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Find clinical trials for Glioblastoma (GBM) in Cleveland, OH

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Cancer
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Cleveland, OH, USA:

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Cleveland, Ohio, United States and 85 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Cleveland, Ohio, United States and 61 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Cleveland, Ohio, United States and 80 other locations

the return of cancer in patients with a newly diagnosed or recurrent glioblastoma multiforme (GBM) in combination with standard che...

Enrolling
Glioblastoma
Biological: Autologous genetically modified gamma-delta T cells
Biological: Allogeneic genetically modified gamma-delta T cells

Phase 1, Phase 2

In8bio

Cleveland, Ohio, United States and 7 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: Temozolomide

Phase 2

Patrick Wen, MD

Cleveland, Ohio, United States and 11 other locations

This multi-site, Phase 1/2a clinical trial is an open label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen o...

Enrolling
Glioblastoma Multiforme
Drug: Perillyl alcohol

Phase 1, Phase 2

NeOnc Technologies

Cleveland, Ohio, United States and 5 other locations

receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...

Enrolling
Advanced Non-Small Cell Squamous Lung Cancer
Epidermal Growth Factor Receptor C797S
Drug: BDTX-1535 monotherapy

Phase 1, Phase 2

Black Diamond Therapeutics

Cleveland, Ohio, United States and 24 other locations

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: Eflornithine (Dose Level 2)

Phase 1

Orbus Therapeutics

Cleveland, Ohio, United States and 7 other locations

This is a phase 2 study of oncolytic polio/rhinovirus recombinant (PVSRIPO) in adult patients with recurrent World Health Organization (WHO) grade IV...

Active, not recruiting
Malignant Glioma
Biological: PVSRIPO

Phase 2

Istari Oncology

Cleveland, Ohio, United States and 5 other locations

* To evaluate the safety and tolerability of escalating doses of ERAS-801 in study participants with recurrent glioblastoma multiforme (GBM...

Active, not recruiting
Glioblastoma Multiforme
Drug: ERAS-801

Phase 1

Erasca

Cleveland, Ohio, United States and 7 other locations

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