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Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Cleveland, Ohio, United States and 61 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Cleveland, Ohio, United States and 27 other locations
the return of cancer in patients with a newly diagnosed or recurrent glioblastoma multiforme (GBM) in combination with standard che...
Phase 1, Phase 2
Cleveland, Ohio, United States and 4 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Cleveland, Ohio, United States and 11 other locations
This multi-site, Phase 1/2a clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen o...
Phase 1, Phase 2
Cleveland, Ohio, United States and 7 other locations
receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...
Phase 1, Phase 2
Cleveland, Ohio, United States and 39 other locations
The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma...
Phase 1
Cleveland, Ohio, United States and 7 other locations
(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main questions it aims to an...
Phase 3
Cleveland, Ohio, United States and 21 other locations
This is a phase 2 study of oncolytic polio/rhinovirus recombinant (PVSRIPO) in adult patients with recurrent World Health Organization (WHO) grade IV...
Phase 2
Cleveland, Ohio, United States and 5 other locations
This study will investigate different doses of \[177Lu\]Lu-NeoB in combination with RT and TMZ in participants with newly diagnosed glioblastoma...
Phase 1
Cleveland, Ohio, United States and 15 other locations
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