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Find clinical trials for Glioblastoma (GBM) in Nashville, TN

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Nashville, TN, USA:

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Nashville, Tennessee, United States and 85 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Nashville, Tennessee, United States and 80 other locations

This is a Phase 1 dose-escalation study of PRT3645, a Cyclin-dependent Kinase 4/6 (CDK4/6) inhibitor, in patients with advanced or metastatic solid t...

Active, not recruiting
Glioblastoma
Endometrial Cancer
Drug: PRT3645

Phase 1

Prelude Therapeutics

Nashville, Tennessee, United States and 12 other locations

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting
Brain Neoplasms
Other: Nivolumab Placebo
Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Nashville, Tennessee, United States and 122 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Nashville, Tennessee, United States and 132 other locations

The purpose of this study is to assess the safety and tolerability of VBI-1901 in subjects with recurrent malignant gliomas (glioblastoma, o...

Enrolling
Glioblastoma Multiforme
Drug: Carmustine
Biological: VBI-1901

Phase 1, Phase 2

VBI Vaccines

Nashville, Tennessee, United States and 10 other locations

This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy o...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: ST101

Phase 1, Phase 2

Sapience Therapeutics

Nashville, Tennessee, United States and 11 other locations

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...

Enrolling
Locally Advanced Solid Tumor
Drug: TNG908

Phase 1, Phase 2

Tango Therapeutics
Tango Therapeutics

Nashville, Tennessee, United States and 11 other locations

To evaluate the safety and tolerability of escalating doses of ERAS-801 in study participants with recurrent glioblastoma multiforme (GBM...

Active, not recruiting
Glioblastoma Multiforme
Drug: ERAS-801

Phase 1

Erasca

Nashville, Tennessee, United States and 7 other locations

Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do cli...

Active, not recruiting
Solid Tumors
Drug: Regorafenib, (Stivarga, BAY73-4506)
Drug: Nivolumab (Opdivo)

Phase 2

Bayer
Bayer

Nashville, Tennessee, United States and 33 other locations

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