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Find clinical trials for Glioblastoma (GBM) in Pittsburgh, PA

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Pittsburgh, PA, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-5401

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 20 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Pittsburgh, Pennsylvania, United States and 61 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Pittsburgh, Pennsylvania, United States and 80 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: Temozolomide

Phase 2

Patrick Wen, MD

Pittsburgh, Pennsylvania, United States and 11 other locations

The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...

Enrolling
Neoplasms
Drug: LCZ696
Drug: [177Lu]-NeoB

Phase 1, Phase 2

Advanced Accelerator Applications

Pittsburgh, Pennsylvania, United States and 13 other locations

A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma...

Enrolling
Glioblastoma
Drug: [177Lu]Lu-DOTA-TATE
Other: Radiotherapy

Phase 1

Novartis
Novartis

Pittsburgh, Pennsylvania, United States and 12 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Pittsburgh, Pennsylvania, United States and 132 other locations

This study will test an investigational drug called AZD1390 in combination with radiation therapy for the treatment of brain tumors. This is the firs...

Enrolling
Recurrent Glioblastoma Multiforme
Primary Glioblastoma Multiforme
Drug: AZD1390
Radiation: Radiation Therapy

Phase 1

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 8 other locations

in male and female patients aged 18 to 69 with newly diagnosed glioblastoma.This treatment will be carried out in addition to the maximal su...

Enrolling
Primary Glioblastoma
Combination Product: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 400 J/cm^2
Combination Product: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 200 J/cm^2

Phase 1, Phase 2

Hemerion Therapeutics

Pittsburgh, Pennsylvania, United States

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