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efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 20 other locations
(SOC) will improve survival in adult patients newly diagnosed with glioblastoma (IDH-wt). It will also evaluate the safety of DOC1021 + pIFN...
Phase 2
Pittsburgh, Pennsylvania, United States and 15 other locations
This is a Phase 3 prospective, randomized, superiority, open-label, multi-site study. The overview of this study is as follows:* A Screening/Baseline...
Phase 3
Pittsburgh, Pennsylvania, United States and 4 other locations
The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma...
Phase 2
Pittsburgh, Pennsylvania, United States and 7 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II...
Phase 2, Phase 3
Pittsburgh, Pennsylvania, United States and 62 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Pittsburgh, Pennsylvania, United States and 90 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Pittsburgh, Pennsylvania, United States and 11 other locations
A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma...
Phase 1
Pittsburgh, Pennsylvania, United States and 13 other locations
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 28 other locations
(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main question it aims to ans...
Phase 3
Pittsburgh, Pennsylvania, United States and 94 other locations
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