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efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 20 other locations
(SOC) will improve survival in adult patients newly diagnosed with glioblastoma (IDH-wt). It will also evaluate the safety of DOC1021 + pIFN...
Phase 2
Pittsburgh, Pennsylvania, United States and 10 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Pittsburgh, Pennsylvania, United States and 61 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Pittsburgh, Pennsylvania, United States and 71 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Pittsburgh, Pennsylvania, United States and 11 other locations
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...
Pittsburgh, Pennsylvania, United States and 132 other locations
A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma...
Phase 1
Pittsburgh, Pennsylvania, United States and 14 other locations
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 28 other locations
(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main questions it aims to an...
Phase 3
Pittsburgh, Pennsylvania, United States and 89 other locations
This study will test an investigational drug called AZD1390 in combination with radiation therapy for the treatment of brain tumors. This is the firs...
Phase 1
Pittsburgh, Pennsylvania, United States and 11 other locations
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