Find clinical trials for Glioblastoma (GBM) in Pittsburgh, PA

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Related conditions:

Glioblastoma

Recurrence

Glioma

Brain Cancer

Astrocytoma

Cancer

Gliosarcoma

Glioblastoma (GBM) trials near Pittsburgh, PA, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting

Glioblastoma

Drug: Temozolomide

Biological: INO-9012

Phase 1, Phase 2

Inovio Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 20 other locations

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling

Glioblastoma

Drug: Temozolomide

Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Pittsburgh, Pennsylvania, United States and 61 other locations

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting

Glioblastoma

Adult-type Diffuse Gliomas

Drug: Pemigatinib

Phase 2

Incyte

Pittsburgh, Pennsylvania, United States and 80 other locations

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling

Glioblastoma

Drug: Neratinib

Drug: Temozolomide

Phase 2

Patrick Wen, MD

Pittsburgh, Pennsylvania, United States and 11 other locations

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-NeoB Lesion Uptake (NeoRay)

The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...

Enrolling

Neoplasms

Drug: [68Ga]-NeoB

Drug: LCZ696

Phase 1, Phase 2

Advanced Accelerator Applications

Pittsburgh, Pennsylvania, United States and 13 other locations

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant with RT & TMZ for the Treatment of Newly Diagnosed GBM (EF-32)

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting

Glioblastoma Multiforme

Device: Optune®

NovoCure

Pittsburgh, Pennsylvania, United States and 132 other locations

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma...

Enrolling

Glioblastoma

Drug: [68Ga]Ga-DOTA-TATE

Other: Temozolomide

Phase 1

Novartis

Pittsburgh, Pennsylvania, United States and 13 other locations

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

This study will test an investigational drug called AZD1390 in combination with radiation therapy for the treatment of brain tumors. This is the firs...

Enrolling

Recurrent Glioblastoma Multiforme

Primary Glioblastoma Multiforme

Radiation: Radiation Therapy

Drug: AZD1390

Phase 1

AstraZeneca

Pittsburgh, Pennsylvania, United States and 11 other locations

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

in male and female patients aged 18 to 69 with newly diagnosed glioblastoma.This treatment will be carried out in addition to the maximal su...

Enrolling

Primary Glioblastoma

Combination Product: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 400 J/cm^2

Combination Product: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 200 J/cm^2

Phase 1, Phase 2

Hemerion Therapeutics

Pittsburgh, Pennsylvania, United States

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Find clinical trials for Glioblastoma (GBM) in .css-epvm6{white-space:nowrap;}Pittsburgh, PA

Related conditions:

Glioblastoma (GBM) trials near Pittsburgh, PA, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-NeoB Lesion Uptake (NeoRay)

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant with RT & TMZ for the Treatment of Newly Diagnosed GBM (EF-32)

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

Find clinical trials for Glioblastoma (GBM) in Pittsburgh, PA