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FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...
Phase 1
St Louis, Missouri, United States and 8 other locations
In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local con...
Phase 4
St Louis, Missouri, United States and 15 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
St Louis, Missouri, United States and 62 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
St Louis, Missouri, United States and 80 other locations
glioma models. Ongoing clinical studies of azeliragon with RT alone and RT plus temozolomide (TMZ) to treat patients with newly diagnosed glioblastoma...
Early Phase 1
St Louis, Missouri, United States
therapy in subjects with newly diagnosed, MGMT promoter unmethylated glioblastoma (GBM).Immune checkpoint blockade, specifically th...
Phase 1
St Louis, Missouri, United States
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
St Louis, Missouri, United States and 28 other locations
(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main question it aims to ans...
Phase 3
St Louis, Missouri, United States and 94 other locations
This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...
Phase 1, Phase 2
St Louis, Missouri, United States and 19 other locations
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