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Find clinical trials for Glioblastoma (GBM) in St Louis, MO

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near St Louis, MO, USA:

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Saint Louis, Missouri, United States and 85 other locations

Locations recently updated

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Biological: ADI-PEG 20
Drug: VT1021

Phase 2, Phase 3

Global Coalition for Adaptive Research

Saint Louis, Missouri, United States and 60 other locations

with or without epacadostat in the treatment of recurrent glioblastoma (GBM). The investigators hypothesize that this combination p...

Active, not recruiting
Glioblastoma
Glioma
Drug: Retifanlimab
Drug: Bevacizumab

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States and 3 other locations

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting
Brain Neoplasms
Other: Nivolumab Placebo
Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Saint Louis, Missouri, United States and 122 other locations

therapy in subjects with newly diagnosed, MGMT promoter unmethylated glioblastoma (GBM).Immune checkpoint blockade, specifically th...

Enrolling
Unmethylated Glioblastoma
Biological: Retifanlimab
Biological: Personalized Neoantigen DNA vaccine

Phase 1

The Washington University
The Washington University

Saint Louis, Missouri, United States

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Saint Louis, Missouri, United States and 132 other locations

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...

Enrolling
Locally Advanced Solid Tumor
Drug: TNG908

Phase 1, Phase 2

Tango Therapeutics
Tango Therapeutics

Saint Louis, Missouri, United States and 11 other locations

receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma multiforme (GBM...

Enrolling
Advanced Non-Small Cell Squamous Lung Cancer
Epidermal Growth Factor Receptor C797S
Drug: BDTX-1535 monotherapy

Phase 1, Phase 2

Black Diamond Therapeutics

Saint Louis, Missouri, United States and 25 other locations

To assess:efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification,...

Enrolling
Glioblastoma Multiforme
Brain Tumor
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Saint Louis, Missouri, United States and 90 other locations

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