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FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...
Early Phase 1
Baltimore, Maryland, United States and 4 other locations
the feasibility of adding MRSI to the evaluation of newly-diagnosed GBM patients treated with standard RT/TMZ and determine whether magnetic...
Phase 2
Baltimore, Maryland, United States and 1 other location
The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...
Phase 1, Phase 2
Baltimore, Maryland, United States and 13 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Baltimore, Maryland, United States and 22 other locations
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...
Baltimore, Maryland, United States and 132 other locations
receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...
Phase 1, Phase 2
Washington, District of Columbia, United States and 24 other locations
This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...
Phase 1, Phase 2
Fairfax, Virginia, United States and 18 other locations
This phase I trial studies the side effects of stereotactic radiosurgery with MBG453 and spartalizumab in treating patients with recurrent glioblastoma...
Phase 1
Baltimore, Maryland, United States and 1 other location
This clinical trial is testing the safety and efficacy of NanO2TM administered via intravenous infusion in combination with standard radiation and ch...
Phase 2
Fairfax, Virginia, United States and 9 other locations
To assess:* efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification...
Phase 2
Silver Spring, Maryland, United States and 90 other locations
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