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Find clinical trials for Heart Disease in Ann Arbor, MI

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Coronary Disease

Heart Disease trials near Ann Arbor, MI, USA:

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE)

non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Device: BrioVAD System
Device: HeartMate 3
BrioHealth Solutions, Inc.

Ann Arbor, Michigan, United States and 16 other locations

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Ann Arbor, Michigan, United States and 66 other locations

A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device performance of the Sapphire...

Enrolling
Coronary Artery Disease
Cardiovascular Diseases
Device: Sapphire 3 Coronary Dilatation Catheter
OrbusNeich

Detroit, Michigan, United States and 13 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Ann Arbor, Michigan, United States and 11 other locations

The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...

Active, not recruiting
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Covidien
Covidien

Ann Arbor, Michigan, United States and 19 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Ann Arbor, Michigan, United States and 39 other locations

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...

Active, not recruiting
Aortic Valve Disease
Aortic Insufficiency
Device: JenaValve Trilogy Heart Valve System
JenaValve Technology

Ann Arbor, Michigan, United States and 29 other locations

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Active, not recruiting
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Detroit, Michigan, United States and 171 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Ann Arbor, Michigan, United States and 84 other locations

The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CH...

Enrolling
Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

Phase 3

Amgen
Amgen

Southfield, Michigan, United States of America and 119 other locations

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