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Find clinical trials for Heart Disease in Boston, MA

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near Boston, MA, USA:

TReatment of Pulmonary Hypertension Group II Study (TROPHY-II)

and will recruit up to 15 patients diagnosed with pulmonary hypertension due to left heart disease that demonstrate combined pre a...

Active, not recruiting
Pulmonary Hypertension (PH) Due to Left Heart Disease
Device: Pulmonary Denervation
SoniVie

Boston, Massachusetts, United States and 2 other locations

The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treati...

Enrolling
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Manchester, New Hampshire, United States and 20 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Boston, Massachusetts, United States and 8 other locations

undergo AVR. Clinical indications will be based upon the 2020 AHA/ACC Clinical Practice Guidelines for Valvular Heart Disease.Seco...

Enrolling
Aortic Stenosis
Behavioral: Physician Notification Letter
Mass General Brigham
Mass General Brigham

Boston, Massachusetts, United States

A phase III study designed as a randomized, within-patient comparison of continuous infusion of diluted Lumason® versus the bolus administration of u...

Not yet enrolling
Heart Diseases
Drug: Lumason
Drug: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]

Phase 3

Bracco
Bracco

Boston, Massachusetts, United States and 2 other locations

Safety and performance evaluation of the preCARDIA System for patients with ADHF.

Enrolling
Acute Heart Failure
Acute Decompensated Heart Failure
Device: preCARDIA system
Abiomed
Abiomed

Boston, Massachusetts, United States and 16 other locations

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Enrolling
Transplant; Failure, Heart
Congenital Heart Disease
Device: EXCOR Active Driving System for Pediatric VAD
Berlin Heart

Boston, Massachusetts, United States and 10 other locations

PumpKIN is a multicenter, prospective, single-arm feasibility study; Evaluating the investigational Jarvik 2015 VAD in pediatric patients with heart...

Active, not recruiting
Pediatric Heart Failure
Device: Surgical placement of the Jarvik 2015 VAD
Procedure: Surgical Placement of Jarvik 2015 VAD

Early Phase 1

Carelon Research

Boston, Massachusetts, United States and 6 other locations

The VITALYST Early Feasibility study (EFS) is designed to evaluate the feasibility and safety of the VITALYST System in subjects undergoing elective...

Enrolling
Heart Disease, Coronary
High-risk Percutaneous Coronary Intervention
Device: VITALYST System
Boston Scientific
Boston Scientific

Boston, Massachusetts, United States and 2 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Boston, Massachusetts, United States and 23 other locations

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