Find clinical trials for Heart Disease in Columbus, OH

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Related conditions:

Heart Diseases

Coronary Artery Disease

Cardiovascular Diseases

Heart Failure

Myocardial Ischemia

Aortic Valve Stenosis

Coronary Disease

Heart Disease trials near Columbus, OH, USA:

ELEVATE-HFpEF Clinical Study

evaluating the safety and efficacy of dual chamber personalized pacing compared to minimal or no pacing for the treatment of patients with heart...

Enrolling

Heart Failure With Preserved Ejection Fraction (HFpEF)

Device: Personalized cardiac pacing

Medtronic

Columbus, Ohio, United States and 8 other locations

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only

Heart Valve Diseases

Aortic Valve Disease

Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System

Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System

Abbott

Columbus, Ohio, United States and 66 other locations

AB-1002 in Patients With Class III Heart Failure (NAN-CS101)

intracoronary infusion of AB-1002 in patients with NYHA Class III heart failure. Patients with non-ischemic cardiomyopathy will be enrolled ...

Active, not recruiting

Heart Disease, Ischemic

Heart Failure, Diastolic

Biological: 3 x 10e13vg AB-1002

Phase 1

AskBio Inc

Columbus, Ohio, United States and 3 other locations

Autus Valve Pivotal Study

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling

Congenital Heart Disease

Device: Pulmonary Valve Replacement Surgery

Autus Valve Technologies

Columbus, Ohio, United States and 11 other locations

Locations recently updated

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2 (FUEL-2)

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling

Single Ventricle Heart Disease

Drug: Placebo

Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Columbus, Ohio, United States and 39 other locations

ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting

Pulmonary Disease

Congenital Heart Disease

Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV

Edwards Lifesciences

Columbus, Ohio, United States and 13 other locations

The JenaValve ALIGN-AR Pivotal Trial

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...

Active, not recruiting

Aortic Valve Disease

Aortic Insufficiency

Device: JenaValve Trilogy Heart Valve System

JenaValve Technology

Columbus, Ohio, United States and 29 other locations

Locations recently updated

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Active, not recruiting

Chronic Kidney Disease

Cardiac Disease

Drug: Placebo

Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals

Columbus, Ohio, United States and 166 other locations

The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study

The purpose of this study is to further evaluate the safety and effectiveness of the Harmony™ TPV system. The Pivotal/CAS phases of the study have tr...

Active, not recruiting

Congenital Heart Disease

Tetrology of Fallot

Device: Harmony TPV System

Medtronic

Columbus, Ohio, United States and 11 other locations