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Find clinical trials for Heart Disease in Columbus, OH

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near Columbus, OH, USA:

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treati...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Columbus, Ohio, United States and 61 other locations

infusion of BNP116.sc-CMV.I1c in patients with NYHA Class III heart failure. Patients with symptomatic congestive heart failure wil...

Enrolling
Heart Disease, Ischemic
Heart Failure, Diastolic
Biological: 3 x 10e13vg NAN-101

Phase 1

Asklepios Biopharmaceutical

Columbus, Ohio, United States and 3 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Columbus, Ohio, United States and 9 other locations

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting
Pulmonary Disease
Congenital Heart Disease
Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Columbus, Ohio, United States and 13 other locations

The purpose of this study is to further evaluate the safety and effectiveness of the Harmony™ TPV system. The Pivotal/CAS phases of the study have tr...

Active, not recruiting
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Medtronic
Medtronic

Columbus, Ohio, United States and 11 other locations

Safety and performance evaluation of the preCARDIA System for patients with ADHF.

Enrolling
Acute Heart Failure
Acute Decompensated Heart Failure
Device: preCARDIA system
Abiomed
Abiomed

Columbus, Ohio, United States and 16 other locations

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...

Active, not recruiting
Aortic Valve Disease
Aortic Insufficiency
Device: JenaValve Trilogy Heart Valve System
JenaValve Technology

Columbus, Ohio, United States and 29 other locations

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Columbus, Ohio, United States and 186 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Enrolling
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Columbus, Ohio, United States and 28 other locations

patients, two dose limiting toxicities were seen including 1 patient with grade 4 neutropenia at the time of disease progression and one wi ...

Enrolling
Primary Central Nervous System Lymphoma
Drug: Durvalumab
Drug: Acalabrutinib

Phase 1

The Washington University
The Washington University

Columbus, Ohio, United States and 1 other location

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