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for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart ...
Phase 2
Greensboro, North Carolina, United States of America and 8 other locations
This study is designed as a repository study to collect resting cardiac phase signals and subject meta data from eligible subjects using the...
Durham, North Carolina, United States and 16 other locations
Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...
Durham, North Carolina, United States and 9 other locations
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...
Durham, North Carolina, United States and 20 other locations
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...
Phase 3
Durham, North Carolina, United States and 30 other locations
Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...
Raleigh, North Carolina, United States and 82 other locations
with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...
Phase 3
Durham, North Carolina, United States and 191 other locations
of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...
Durham, North Carolina, United States and 56 other locations
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failin...
Raleigh, North Carolina, United States and 50 other locations
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...
Durham, North Carolina, United States and 103 other locations
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