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for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart ...
Phase 2
Greensboro, North Carolina, United States of America and 8 other locations
Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...
Durham, North Carolina, United States and 9 other locations
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...
Phase 3
Durham, North Carolina, United States and 26 other locations
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...
Durham, North Carolina, United States and 19 other locations
Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...
Raleigh, North Carolina, United States and 71 other locations
of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...
Durham, North Carolina, United States and 56 other locations
subjects using the Phase Signal Recorder (PSR) prior to Right Heart Cath (RHC). The repository data will be used for the purposes of researc...
Durham, North Carolina, United States and 16 other locations
of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...
Henrico, Virginia, United States and 69 other locations
This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with c...
Raleigh, North Carolina, United States and 76 other locations
The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...
Phase 3
Chapel Hill, North Carolina, United States and 468 other locations
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