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Find clinical trials for Heart Disease in Durham, NC

CTV is a public benefit provided by Veeva Systems to help you find the most relevant clinical trials for you and your loved ones

Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Aortic Valve Stenosis
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Heart Disease trials near Durham, NC, USA:

for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart ...

Enrolling
Coronary Heart Disease
Drug: DFV890
Drug: Placebo

Phase 2

N
Novartis

Greensboro, North Carolina, United States of America and 8 other locations

This study is designed as a repository study to collect resting cardiac phase signals and subject meta data from eligible subjects using the...

Active, not recruiting
Cardiac Disease
Right Heart Failure
Device: CorVista Capture
Analytics For Life

Durham, North Carolina, United States and 16 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Durham, North Carolina, United States and 9 other locations

The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...

Enrolling
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
C
Covidien

Durham, North Carolina, United States and 20 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Durham, North Carolina, United States and 30 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
P
Philips

Raleigh, North Carolina, United States and 82 other locations

VictORION-INCLUSION (V-INCLUSION) seeks to evaluate the effectiveness of inclisiran as an innovative therapy with the potential to help bridge care g...

Enrolling
Atherosclerotic Cardiovascular Disease
Drug: Inclisiran

Phase 4

D
Duke University

Chapel Hill, North Carolina, United States and 2 other locations

Locations recently updated

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

A
Alexion Pharmaceuticals

Durham, North Carolina, United States and 199 other locations

of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Durham, North Carolina, United States and 56 other locations

This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failin...

Enrolling
Aortic Stenosis, Severe
Aortic Stenosis
Device: Edwards SAPIEN 3/SAPIEN 3 Ultra THV
E
Edwards Lifesciences

Raleigh, North Carolina, United States and 51 other locations