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Find clinical trials for Heart Disease in Durham, NC

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Myocardial Ischemia
Heart Failure
Coronary Disease
Hypertension

Heart Disease trials near Durham, NC, USA:

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease

for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart ...

Enrolling
Coronary Heart Disease
Drug: Placebo
Drug: DFV890

Phase 2

Novartis
Novartis

Greensboro, North Carolina, United States and 4 other locations

The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...

Enrolling
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Covidien
Covidien

Durham, North Carolina, United States and 18 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Raleigh, North Carolina, United States and 71 other locations

of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...

Enrolling
Heart Valve Diseases
Cardiovascular Diseases
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System
Cardiac Dimensions

Henrico, Virginia, United States and 61 other locations

subjects using the Phase Signal Recorder (PSR) prior to Right Heart Cath (RHC). The repository data will be used for the purposes of researc...

Active, not recruiting
Cardiac Disease
Right Heart Failure
Device: CorVista Capture
Analytics For Life

Durham, North Carolina, United States and 16 other locations

of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Durham, North Carolina, United States and 62 other locations

This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with c...

Active, not recruiting
Heart Diseases
Aortic Stenosis, Severe
Device: Edwards SAPIEN 3 / SAPIEN 3 Ultra THV
Edwards Lifesciences
Edwards Lifesciences

Raleigh, North Carolina, United States and 76 other locations

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Chapel Hill, North Carolina, United States and 467 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Durham, North Carolina, United States and 84 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Durham, North Carolina, United States and 103 other locations

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