Find clinical trials for Heart Disease in Jacksonville, FL

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Related conditions:

Heart Diseases

Coronary Artery Disease

Cardiovascular Diseases

Heart Failure

Myocardial Ischemia

Coronary Disease

Kidney Diseases

Heart Disease trials near Jacksonville, FL, USA:

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study ...

Active, not recruiting

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

Drug: NNC6019-0001

Drug: Placebo (NNC6019-0001)

Phase 2

Novo Nordisk

Jacksonville, Florida, United States and 32 other locations

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe ...

Enrolling

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

Drug: NNC6019-0001

Phase 2

Novo Nordisk

Jacksonville, Florida, United States and 30 other locations

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting

Ischemic Heart Disease

Coronary Artery Disease

Device: Orbital Atherectomy

Device: Balloon

Abbott

Jacksonville, Florida, United States and 103 other locations

Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF)

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling

Cardiovascular Diseases

Heart Failure Preserved Ejection Fraction

Drug: Placebo

Drug: Tovinontrine (CRD-750

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 62 other locations

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling

Mitral Valve Regurgitation

Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)

Covidien

Jacksonville, Florida, United States of America and 84 other locations

A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling

Cardiovascular Diseases

Heart Failure With Reduced Ejection Fraction

Drug: Tovinontrine (CRD-750)

Drug: Placebo

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 82 other locations

Firehawk Rapamycin Target Eluting Coronary Stent North American Trial (TARGET-IV_NA)

2nd generation DES for the treatment of subjects with ischemic heart disease (NSTEMI, recent STEMI (\>24 hours from initial present...

Active, not recruiting

Coronary Artery Disease

Device: 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent)

Device: Microport Firehawk stent

MicroPort

Jacksonville, Florida, United States and 56 other locations

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (TRANSFORM)

who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests...

Enrolling

Diabetes Mellitus, Type 2

Metabolic Syndrome

Device: The Cleerly CAD Staging System

Cleerly

Jacksonville, Florida, United States and 60 other locations

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function (PROTECT IV)

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling

Coronary Artery Disease

Left Ventricular Dysfunction

Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®

Device: IABP Intra-aortic balloon pump

Abiomed

Jacksonville, Florida, United States and 133 other locations

Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

While there are several completed clinical trials that address treatment strategy in patients with symptomatic and recurrent AF, there are no randomi...

Active, not recruiting

Atrial Fibrillation

Drug: Dronedarone

Phase 4

American Heart Association (AHA)

Jacksonville, Florida, United States and 102 other locations

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Find clinical trials for Heart Disease in .css-epvm6{white-space:nowrap;}Jacksonville, FL

Related conditions:

Heart Disease trials near Jacksonville, FL, USA:

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF)

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)

Firehawk Rapamycin Target Eluting Coronary Stent North American Trial (TARGET-IV_NA)

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (TRANSFORM)

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function (PROTECT IV)

Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

Find clinical trials for Heart Disease in Jacksonville, FL