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Find clinical trials for Heart Disease in Jacksonville, FL

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Related conditions:

Heart Diseases
Coronary Artery Disease
Heart Failure
Cardiovascular Diseases
Myocardial Ischemia
Coronary Disease
Aortic Valve Stenosis

Heart Disease trials near Jacksonville, FL, USA:

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 (Re-PHIRE)

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Active, not recruiting
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

Jacksonville, Florida, United States and 60 other locations

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study ...

Active, not recruiting
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: NNC6019-0001
Drug: Placebo (NNC6019-0001)

Phase 2

Novo Nordisk
Novo Nordisk

Jacksonville, Florida, United States and 33 other locations

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe ...

Enrolling
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: NNC6019-0001

Phase 2

Novo Nordisk
Novo Nordisk

Jacksonville, Florida, United States and 32 other locations

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a stic...

Enrolling
Heart Diseases
Transthyretin Amyloidosis
Drug: Placebo oral tablet
Drug: Acoramidis

Phase 3

Eidos Therapeutics

Jacksonville, Florida, United States and 21 other locations

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Jacksonville, Florida, United States and 103 other locations

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Jacksonville, Florida, United States of America and 84 other locations

Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF)

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure Preserved Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 84 other locations

A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure With Reduced Ejection Fraction
Drug: Tovinontrine (CRD-750)
Drug: Placebo

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 128 other locations

Firehawk Rapamycin Target Eluting Coronary Stent North American Trial (TARGET-IV_NA)

2nd generation DES for the treatment of subjects with ischemic heart disease (NSTEMI, recent STEMI (\>24 hours from initial present...

Active, not recruiting
Coronary Artery Disease
Device: 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent)
Device: Microport Firehawk stent
MicroPort

Jacksonville, Florida, United States and 56 other locations

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (TRANSFORM)

who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System
Cleerly

Jacksonville, Florida, United States and 81 other locations

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