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Find clinical trials for Heart Disease in Jacksonville, FL

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near Jacksonville, FL, USA:

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease

for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart ...

Enrolling
Coronary Heart Disease
Drug: DFV890
Drug: Placebo

Phase 2

Novartis
Novartis

Jacksonville, Florida, United States and 8 other locations

This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study ...

Active, not recruiting
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: NNC6019-0001
Drug: Placebo (NNC6019-0001)

Phase 2

Novo Nordisk
Novo Nordisk

Jacksonville, Florida, United States and 30 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure Preserved Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 8 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure With Reduced Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750)

Phase 2

Cardurion Pharmaceuticals

Jacksonville, Florida, United States and 9 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Jacksonville, Florida, United States of America and 84 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Jacksonville, Florida, United States and 103 other locations

This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe ...

Enrolling
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: NNC6019-0001

Phase 2

Novo Nordisk
Novo Nordisk

Jacksonville, Florida, United States and 22 other locations

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

Jacksonville, Florida, United States and 123 other locations

reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart F...

Active, not recruiting
Heart Failure
Other: Placebo
Drug: Finerenone (BAY94-8862)

Phase 3

Bayer
Bayer

Saint Augustine, Florida, United States and 665 other locations

Locations recently updated

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Enrolling
Cardiovascular Disease
Drug: Semaglutide
Drug: Cagrilintide

Phase 3

Novo Nordisk
Novo Nordisk

Fleming Island, Florida, United States and 553 other locations

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