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Find clinical trials for Heart Disease in London, England

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near London, England, GBR:

PROTEUS: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease

PROTEUS is a multicentre, two arm, randomised controlled trial of a medical device to assess the impact of the introduction of EchoGo into the standa...

Active, not recruiting
Coronary Heart Disease
Diagnostic Test: EchoGo
Ultromics

London, United Kingdom and 19 other locations

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Enrolling
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

London, United Kingdom and 64 other locations

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting
Ischemic Heart Disease
Ischaemic Heart Disease
Procedure: Angiographic guided PCI
Procedure: OCT guided PCI
Aarhus University Hospital Skejby

London, United Kingdom and 37 other locations

Familial Hypercholesterolemia (HeFH) or Premature Coronary Artery Disease (CAD) Who Require Additional Lowering of LDL-C. VERVE-102 Uses Bas...

Enrolling
Premature Coronary Heart Disease
Heterozygous Familial Hypercholesterolemia
Drug: VERVE-102

Phase 1

Verve Therapeutics

London, United Kingdom and 2 other locations

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic h...

Active, not recruiting
Heart Transplantation
Device: XVIVO heart preservation devices
Device: Standard ICSS
XVIVO
XVIVO

Cambridge, United Kingdom and 14 other locations

Evaluation of TAVR using the NAVITOR valve in a Global Investigation.

Enrolling
Symptomatic Severe Aortic Stenosis
Device: Navitor Transcatheter Aortic Valve and FlexNav Delivery System
Abbott
Abbott

London, United Kingdom and 37 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

London, United Kingdom and 82 other locations

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

London, United Kingdom and 186 other locations

Hypertrophic Cardiomyopathy (HCM) is an inherited heart condition. Most people who have it are unaware of any problems relating to it. Unfor...

Enrolling
Hypertrophic Cardiomyopathy
Diagnostic Test: Non-invasive ECG imaging - CardioInsight test
Imperial College London
Imperial College London

London, United Kingdom

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

London, United Kingdom and 131 other locations

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