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Find clinical trials for Heart Disease in London, England

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near London, England, GBR:

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 (Re-PHIRE)

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Enrolling
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

London, United Kingdom and 63 other locations

PROTEUS is a multicentre, two arm, randomised controlled trial of a medical device to assess the impact of the introduction of EchoGo into the standa...

Active, not recruiting
Coronary Heart Disease
Diagnostic Test: EchoGo
Ultromics

London, United Kingdom and 19 other locations

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting
Ischemic Heart Disease
Ischaemic Heart Disease
Procedure: Angiographic guided PCI
Procedure: OCT guided PCI
Aarhus University Hospital Skejby

London, United Kingdom and 37 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

London, United Kingdom and 71 other locations

Evaluation of TAVR using the NAVITOR valve in a Global Investigation.

Enrolling
Symptomatic Severe Aortic Stenosis
Device: Navitor Transcatheter Aortic Valve and FlexNav Delivery System
Abbott
Abbott

London, United Kingdom and 37 other locations

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

London, United Kingdom and 468 other locations

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic h...

Active, not recruiting
Heart Transplantation
Device: XVIVO heart preservation devices
Device: Standard ICSS
XVIVO
XVIVO

Cambridge, United Kingdom and 14 other locations

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

London, United Kingdom and 123 other locations

reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart F...

Active, not recruiting
Heart Failure
Other: Placebo
Drug: Finerenone (BAY94-8862)

Phase 3

Bayer
Bayer

Stevenage, Hertfordshire, United Kingdom and 665 other locations

Locations recently updated

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Enrolling
Cardiovascular Disease
Drug: Semaglutide
Drug: Cagrilintide

Phase 3

Novo Nordisk
Novo Nordisk

London, United Kingdom and 553 other locations

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