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Find clinical trials for Heart Disease in Los Angeles, CA

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Myocardial Ischemia
Heart Failure
Coronary Disease
Hypertension

Heart Disease trials near Los Angeles, CA, USA:

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 (Re-PHIRE)

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Enrolling
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

Los Angeles, California, United States and 63 other locations

The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treati...

Enrolling
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Thousand Oaks, California, United States and 20 other locations

This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study ...

Active, not recruiting
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: NNC6019-0001
Drug: Placebo (NNC6019-0001)

Phase 2

Novo Nordisk
Novo Nordisk

Beverly Hills, California, United States and 30 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure Preserved Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750

Phase 2

Cardurion Pharmaceuticals

Van Nuys, California, United States and 9 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Enrolling
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Los Angeles, California, United States and 4 other locations

of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart...

Enrolling
Cardiovascular Diseases
Heart Failure With Reduced Ejection Fraction
Drug: Placebo
Drug: Tovinontrine (CRD-750)

Phase 2

Cardurion Pharmaceuticals

Beverly Hills, California, United States and 10 other locations

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Enrolling
Transplant; Failure, Heart
Congenital Heart Disease
Device: EXCOR Active Driving System for Pediatric VAD
Berlin Heart

Los Angeles, California, United States and 10 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Udenafil
Drug: Placebo

Phase 3

Mezzion Pharmaceuticals

Los Angeles, California, United States and 21 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Enrolling
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Los Angeles, California, United States and 27 other locations

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting
Pulmonary Disease
Congenital Heart Disease
Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Los Angeles, California, United States and 13 other locations

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