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Find clinical trials for Heart Disease in Louisville, KY

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Heart Failure
Coronary Artery Disease
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near Louisville, KY, USA:

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE)

non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Device: BrioVAD System
Device: HeartMate 3
BrioHealth Solutions, Inc.

Louisville, Kentucky, United States and 36 other locations

evaluating the safety and efficacy of dual chamber personalized pacing compared to minimal or no pacing for the treatment of patients with heart...

Enrolling
Heart Failure With Preserved Ejection Fraction (HFpEF)
Device: Personalized cardiac pacing
Medtronic
Medtronic

Louisville, Kentucky, United States and 49 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Louisville, Kentucky, United States and 73 other locations

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardia...

Enrolling
Atherosclerotic Coronary Vascular Disease
Coronary Arterial Disease (CAD)
Drug: Placebo
Drug: Orticumab

Phase 2

Abcentra

Louisville, Kentucky, United States and 40 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Louisville, Kentucky, United States and 103 other locations

safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Other: Guideline Medical Directed Therapy
Device: HeartMate 3 Left Ventricular Assist System
Abbott
Abbott

Louisville, Kentucky, United States and 67 other locations

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Active, not recruiting
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

Louisville, Kentucky, United States and 112 other locations

The goal of this clinical trial is to is to test the safety of a new way to deliver a commonly used drug (amiodarone) used in heart surgery ...

Enrolling
Atrial Fibrillation, Postoperative
Combination Product: The intervention includes Amiodarone-Infused CardiaMend patches (70mg, 150mg and 300mg)

Phase 1, Phase 2

Helios Cardio Inc.

Louisville, Kentucky, United States

who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System
Cleerly

Louisville, Kentucky, United States and 125 other locations

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications o...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Louisville, Kentucky, United States and 762 other locations

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