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Find clinical trials for Heart Disease in Louisville, KY

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near Louisville, KY, USA:

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE)

non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Device: BrioVAD System
Device: HeartMate 3
BrioHealth Solutions, Inc.

Louisville, Kentucky, United States and 31 other locations

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardia...

Enrolling
Atherosclerotic Coronary Vascular Disease
Coronary Arterial Disease (CAD)
Drug: Placebo
Drug: Orticumab

Phase 2

Abcentra

Louisville, Kentucky, United States and 40 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Louisville, Kentucky, United States and 73 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Louisville, Kentucky, United States and 103 other locations

safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Other: Guideline Medical Directed Therapy
Device: HeartMate 3 Left Ventricular Assist System
Abbott
Abbott

Louisville, Kentucky, United States and 62 other locations

The goal of this clinical trial is to is to test the safety of a new way to deliver a commonly used drug (amiodarone) used in heart surgery ...

Enrolling
Atrial Fibrillation, Postoperative
Combination Product: The intervention includes Amiodarone-Infused CardiaMend patches (70mg, 150mg and 300mg)

Phase 1, Phase 2

Helios Cardio Inc.

Louisville, Kentucky, United States

who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System
Cleerly

Louisville, Kentucky, United States and 114 other locations

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications o...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Louisville, Kentucky, United States and 765 other locations

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Active, not recruiting
Cardiovascular Disease
Drug: Cagrilintide
Drug: Semaglutide

Phase 3

Novo Nordisk
Novo Nordisk

Louisville, Kentucky, United States and 631 other locations

The primary objective of this trial is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

Phase 3

Amgen
Amgen

Louisville, Kentucky, United States and 742 other locations

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