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Find clinical trials for Heart Disease in Philadelphia, PA

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near Philadelphia, PA, USA:

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Enrolling
Transplant; Failure, Heart
Congenital Heart Disease
Device: EXCOR Active Driving System for Pediatric VAD
Berlin Heart

Philadelphia, Pennsylvania, United States and 10 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Philadelphia, Pennsylvania, United States and 23 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Enrolling
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Philadelphia, Pennsylvania, United States and 27 other locations

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting
Pulmonary Disease
Congenital Heart Disease
Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Philadelphia, Pennsylvania, United States and 13 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Wynnewood, Pennsylvania, United States and 71 other locations

The purpose of this study is to further evaluate the safety and effectiveness of the Harmony™ TPV system. The Pivotal/CAS phases of the study have tr...

Active, not recruiting
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Medtronic
Medtronic

Philadelphia, Pennsylvania, United States and 11 other locations

of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Philadelphia, Pennsylvania, United States and 56 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Philadelphia, Pennsylvania, United States and 74 other locations

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...

Active, not recruiting
Aortic Valve Disease
Aortic Insufficiency
Device: JenaValve Trilogy Heart Valve System
JenaValve Technology

Wynnewood, Pennsylvania, United States and 29 other locations

of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...

Enrolling
Heart Valve Diseases
Cardiovascular Diseases
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System
Cardiac Dimensions

Philadelphia, Pennsylvania, United States and 69 other locations

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