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Find clinical trials for Heart Disease in Pittsburgh, PA

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Heart Failure
Coronary Artery Disease
Myocardial Ischemia
Aortic Valve Stenosis
Heart Valve Diseases

Heart Disease trials near Pittsburgh, PA, USA:

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Pittsburgh, Pennsylvania, United States and 107 other locations

The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recov...

Not yet enrolling
Heart Failure
Reduced Ejection Fraction Heart Failure
Device: Impella 5.5 SmartAssist
Abiomed
Abiomed

Pittsburgh, Pennsylvania, United States and 14 other locations

of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).The study contains of 5 a...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Pittsburgh, Pennsylvania, United States and 50 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Pittsburgh, Pennsylvania, United States and 73 other locations

safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Other: Guideline Medical Directed Therapy
Device: HeartMate 3 Left Ventricular Assist System
Abbott
Abbott

Pittsburgh, Pennsylvania, United States and 67 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Active, not recruiting
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Pittsburgh, Pennsylvania, United States and 31 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 39 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Pittsburgh, Pennsylvania, United States and 84 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Pittsburgh, Pennsylvania, United States and 83 other locations

subjects using the Phase Signal Recorder (PSR) prior to Right Heart Cath (RHC). The repository data will be used for the purposes of researc...

Active, not recruiting
Cardiac Disease
Right Heart Failure
Device: CorVista Capture
Analytics For Life

Pittsburgh, Pennsylvania, United States and 16 other locations

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