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Find clinical trials for Heart Disease in Roma, Lazio

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Coronary Disease
Hypertension

Heart Disease trials near Roma, Lazio, ITA:

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting
Ischemic Heart Disease
Ischaemic Heart Disease
Procedure: Angiographic guided PCI
Procedure: OCT guided PCI
Aarhus University Hospital Skejby

Rome, Italy and 37 other locations

Purpose of this prospective, randomized, controlled, multi-center study is to evaluate the safety and efficacy of Transcatheter Aortic Valve Implanta...

Active, not recruiting
Heart Valve Diseases
Aortic Valve Stenosis
Procedure: Transcatheter aortic valve replacement
Optimapharm

Roma, Italy and 47 other locations

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Roma, Italy and 468 other locations

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

Rome, RM, Italy and 126 other locations

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Enrolling
Cardiovascular Disease
Drug: Semaglutide
Drug: Cagrilintide

Phase 3

Novo Nordisk
Novo Nordisk

Roma, Italy and 576 other locations

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...

Active, not recruiting
Coronary Heart Disease (CHD)
Drug: Evolocumab
Drug: Placebo

Phase 3

Amgen
Amgen

Roma, Italy and 851 other locations

TripleTRE investigates the effect of initial triple combination therapy (oral endothelin receptor antagonist (ERA) + oral phosphodiesterase tyüe-5 in...

Enrolling
Pulmonary Arterial Hypertension
Drug: Generic treprostinil sodium + Standard of Care (Double Oral)
Drug: Standard of Care - Double Oral

Phase 4

AOP Orphan

Rome, Lazio, Italy and 18 other locations

Patients presenting with idiopathic dilated cardiomyopathy and left ventricle dysfunction (LVEF \<40%), naive of anti-remodeling cardiac medical ther...

Enrolling
Heart Failure
Left Ventricular Dysfunction
Diagnostic Test: Thermodilution based assessment of coronary microcirculation
Integrated University Hospital Trust of Verona

Roma, Italy and 8 other locations

of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) ...

Enrolling
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)
Allogeneic Hematopoietic Cell Transplant
Biological: tabelecleucel

Phase 3

Atara Biotherapeutics

Roma, Italy and 70 other locations

The objective of this study is to evaluate the effects of sotatercept (MK-7962, formerly called ACE-011) treatment (plus maximum tolerated background...

Active, not recruiting
Pulmonary Arterial Hypertension
Drug: Sotatercept
Other: Placebo

Phase 3

Acceleron Pharma
Acceleron Pharma

Roma, Italy and 56 other locations

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