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Find clinical trials for Heart Disease in Roma, Lazio

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near Roma, Lazio, ITA:

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting
Ischemic Heart Disease
Ischaemic Heart Disease
Procedure: Angiographic guided PCI
Procedure: OCT guided PCI
Aarhus University Hospital Skejby

Rome, Italy and 37 other locations

The purpose is to investigate if a strategy of routine OCT based diagnosis and guidance of PCI improves clinical outcomes compared with a standard st...

Invitation-only
Ischemic Coronary Artery Disease
Ischemic Heart Disease
Procedure: OCT Guided PCI
Procedure: Angiographic Guided PCI
Aarhus University Hospital Skejby

Rome, Italy and 18 other locations

The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with...

Active, not recruiting
Persistent Atrial Fibrillation
Device: FARAPULSE™ Pulsed Field Ablation (PFA) System
Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific
Boston Scientific

Roma, Italy and 61 other locations

Purpose of this prospective, randomized, controlled, multi-center study is to evaluate the safety and efficacy of Transcatheter Aortic Valve Implanta...

Active, not recruiting
Heart Valve Diseases
Aortic Valve Stenosis
Procedure: Transcatheter aortic valve replacement
Optimapharm

Roma, Italy and 48 other locations

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Active, not recruiting
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump
Abiomed
Abiomed

Rome, RM, Italy and 103 other locations

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a stic...

Enrolling
Heart Diseases
Transthyretin Amyloidosis
Drug: Placebo oral tablet
Drug: Acoramidis

Phase 3

Eidos Therapeutics

Rome, Italy and 93 other locations

TripleTRE investigates the effect of initial triple combination therapy (oral endothelin receptor antagonist (ERA) + oral phosphodiesterase tyüe-5 in...

Enrolling
Pulmonary Arterial Hypertension
Drug: Generic treprostinil sodium + Standard of Care (Double Oral)
Drug: Standard of Care - Double Oral

Phase 4

AOP Orphan

Rome, Lazio, Italy and 18 other locations

with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Participation...

Enrolling
Chronic Kidney Disease
Atherosclerosis Cardiovascular Disease
Drug: Orforglipron
Drug: Placebo

Phase 3

Lilly
Lilly

Roma, Italy and 558 other locations

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications o...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Roma, Italy and 765 other locations

whether a medicine called BI 690517 helps people with chronic kidney disease when taken in combination with a study medicine called empaglif ...

Enrolling
Kidney Disease, Chronic
Drug: Placebo matching BI 690517
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Roma, Italy and 399 other locations

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