Find clinical trials for Heart Disease in Roma, Lazio

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Related conditions:

Heart Diseases

Coronary Artery Disease

Cardiovascular Diseases

Heart Failure

Myocardial Ischemia

Coronary Disease

Hypertension

Heart Disease trials near Roma, Lazio, ITA:

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting

Ischemic Heart Disease

Ischaemic Heart Disease

Procedure: Angiographic guided PCI

Procedure: OCT guided PCI

Aarhus University Hospital Skejby

Rome, Italy and 37 other locations

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis)

Purpose of this prospective, randomized, controlled, multi-center study is to evaluate the safety and efficacy of Transcatheter Aortic Valve Implanta...

Active, not recruiting

Heart Valve Diseases

Aortic Valve Stenosis

Procedure: Transcatheter aortic valve replacement

Optimapharm

Roma, Italy and 47 other locations

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

TripleTRE investigates the effect of initial triple combination therapy (oral endothelin receptor antagonist (ERA) + oral phosphodiesterase tyüe-5 in...

Enrolling

Pulmonary Arterial Hypertension

Drug: Generic treprostinil sodium + Standard of Care (Double Oral)

Drug: Standard of Care - Double Oral

Phase 4

AOP Orphan

Rome, Lazio, Italy and 18 other locations

Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation (AVANTGUARD)

The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with...

Enrolling

Persistent Atrial Fibrillation

Device: FARAPULSE™ Pulsed Field Ablation (PFA) System

Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone

Boston Scientific

Rome, Italy and 72 other locations

Impella®-Supported PCI in High-Risk Patients with Complex Coronary Artery Disease and Reduced Left Ventricular Function (PROTECT IV)

2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart...

Enrolling

Coronary Artery Disease

Left Ventricular Dysfunction

Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®

Device: IABP Intra-aortic balloon pump

Abiomed

Rome, RM, Italy and 131 other locations

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke (VESALIUS-CV)

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...

Active, not recruiting

Coronary Heart Disease (CHD)

Drug: Evolocumab

Drug: Placebo

Phase 3

Amgen

Roma, Italy and 851 other locations

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Enrolling

Cardiovascular Disease

Drug: Semaglutide

Drug: Cagrilintide

Phase 3

Novo Nordisk

Roma, Italy and 587 other locations

Locations recently updated

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

cardiovascular events (MACE) including coronary heart disease (CHD) death, ischemic stroke, myocardial infarction (MI), acute limb...

Enrolling

Arteriosclerosis

Hypercholesterolaemia

Drug: Placebo

Drug: Enlicitide Decanoate

Phase 3

Merck Sharp & Dohme (MSD)

Roma, Lazio, Italy and 609 other locations

Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling (MICROREV)

Patients presenting with idiopathic dilated cardiomyopathy and left ventricle dysfunction (LVEF \<40%), naive of anti-remodeling cardiac med...

Enrolling

Heart Failure

Left Ventricular Dysfunction

Diagnostic Test: Thermodilution based assessment of coronary microcirculation

Integrated University Hospital Trust of Verona

Roma, Italy and 8 other locations

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease...

Active, not recruiting

Atherosclerotic Cardiovascular Disease

Drug: Olpasiran

Drug: Placebo

Phase 3

Amgen

Roma, Italy and 736 other locations

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Find clinical trials for Heart Disease in .css-epvm6{white-space:nowrap;}Roma, Lazio

Related conditions:

Heart Disease trials near Roma, Lazio, ITA:

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis)

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation (AVANTGUARD)

Impella®-Supported PCI in High-Risk Patients with Complex Coronary Artery Disease and Reduced Left Ventricular Function (PROTECT IV)

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke (VESALIUS-CV)

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling (MICROREV)

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

Find clinical trials for Heart Disease in Roma, Lazio