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Find clinical trials for Heart Disease in San Diego, CA

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Coronary Disease

Heart Disease trials near San Diego, CA, USA:

TReatment of Pulmonary Hypertension Group II Study (TROPHY-II)

and will recruit up to 15 patients diagnosed with pulmonary hypertension due to left heart disease that demonstrate combined pre a...

Active, not recruiting
Pulmonary Hypertension (PH) Due to Left Heart Disease
Device: Pulmonary Denervation
SoniVie

San Diego, California, United States and 2 other locations

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Active, not recruiting
Heart Failure
Pulmonary Hypertension (World Health Organization Group 2)
Drug: AZD3427
Drug: Placebo

Phase 2

AstraZeneca
AstraZeneca

La Jolla, California, United States and 59 other locations

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

La Jolla, California, United States and 60 other locations

The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CH...

Enrolling
Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

Phase 3

Amgen
Amgen

San Diego, California, United States and 55 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

San Diego, California, United States and 39 other locations

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...

Active, not recruiting
Aortic Valve Disease
Aortic Insufficiency
Device: JenaValve Trilogy Heart Valve System
JenaValve Technology

San Diego, California, United States and 29 other locations

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

San Diego, California, United States and 73 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

La Jolla, California, United States and 103 other locations

Locations recently updated

of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...

Enrolling
Heart Valve Diseases
Cardiovascular Diseases
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System
Cardiac Dimensions

San Diego, California, United States and 71 other locations

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a stic...

Enrolling
Heart Diseases
Transthyretin Amyloidosis
Drug: Placebo oral tablet
Drug: Acoramidis

Phase 3

Eidos Therapeutics

La Jolla, California, United States and 37 other locations

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