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and will recruit up to 15 patients diagnosed with pulmonary hypertension due to left heart disease that demonstrate combined pre a...
San Diego, California, United States and 2 other locations
is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...
Phase 2
La Jolla, California, United States and 59 other locations
) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...
La Jolla, California, United States and 60 other locations
The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CH...
Phase 3
San Diego, California, United States and 55 other locations
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...
Phase 3
San Diego, California, United States and 39 other locations
To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...
San Diego, California, United States and 29 other locations
open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...
San Diego, California, United States and 73 other locations
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...
La Jolla, California, United States and 103 other locations
of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...
San Diego, California, United States and 71 other locations
Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a stic...
Phase 3
La Jolla, California, United States and 37 other locations
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