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Find clinical trials for Heart Disease in St Louis, MO

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Heart Failure
Coronary Artery Disease
Myocardial Ischemia
Aortic Valve Stenosis
Heart Valve Diseases

Heart Disease trials near St Louis, MO, USA:

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE)

non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Device: BrioVAD System
Device: HeartMate 3
BrioHealth Solutions, Inc.

St Louis, Missouri, United States and 46 other locations

The goal of this clinical trial is to validate performance claims for method comparison for ABL90 FLEX PLUS in heparinized neonatal arterial, venous,...

Enrolling
Congenital Heart Disease
Device: method comparison
Radiometer

Saint Louis, Missouri, United States

The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recov...

Not yet enrolling
Heart Failure
Reduced Ejection Fraction Heart Failure
Device: Impella 5.5 SmartAssist
Abiomed
Abiomed

St Louis, Missouri, United States and 14 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Active, not recruiting
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Saint Louis, Missouri, United States and 31 other locations

To assess the safety and effectiveness of the SAPIEN 3 transcatheter heart valve in patients with a failing mitral bioprosthetic valve....

Active, not recruiting
Mitral Valve Disease
Heart Failure
Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX
Edwards Lifesciences
Edwards Lifesciences

St Louis, Missouri, United States and 11 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

St Louis, Missouri, United States and 39 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

St Louis, Missouri, United States and 84 other locations

VictORION-INCLUSION (V-INCLUSION) seeks to evaluate the effectiveness of inclisiran as an innovative therapy with the potential to help bridge care g...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Inclisiran

Phase 4

Duke University
Duke University

St Louis, Missouri, United States and 24 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Saint Louis, Missouri, United States and 83 other locations

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Invitation-only
Transplant; Failure, Heart
Congenital Heart Disease
Device: EXCOR Active Driving System for Pediatric VAD
Berlin Heart

St Louis, Missouri, United States and 16 other locations

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