Find clinical trials for Heart Disease in St Louis, MO

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Related conditions:

Heart Diseases

Coronary Artery Disease

Cardiovascular Diseases

Myocardial Ischemia

Heart Failure

Coronary Disease

Hypertension

Heart Disease trials near St Louis, MO, USA:

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 (Re-PHIRE)

is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...

Enrolling

Heart Failure

Pulmonary Hypertension (World Health Organization Group 2)

Drug: AZD3427

Drug: Placebo

Phase 2

AstraZeneca

Saint Louis, Missouri, United States and 63 other locations

ABL90 FP MC Neonatal Arterial, Venous, Capillary Blood

The goal of this clinical trial is to validate performance claims for method comparison for ABL90 FLEX PLUS in heparinized neonatal arterial, venous,...

Enrolling

Congenital Heart Disease

Device: method comparison

Radiometer

Saint Louis, Missouri, United States

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Enrolling

Transplant; Failure, Heart

Congenital Heart Disease

Device: EXCOR Active Driving System for Pediatric VAD

Berlin Heart

Saint Louis, Missouri, United States and 10 other locations

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2 (FUEL-2)

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling

Single Ventricle Heart Disease

Drug: Udenafil

Drug: Placebo

Phase 3

Mezzion Pharmaceuticals

Saint Louis, Missouri, United States and 21 other locations

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD (ASCENT ASD)

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Enrolling

Heart Defects, Congenital

Cardiovascular Diseases

Device: reSept ASD Occluder

atHeart Medical

Saint Louis, Missouri, United States and 27 other locations

PARTNER 3 Trial - Mitral Valve in Valve

To assess the safety and effectiveness of the SAPIEN 3 transcatheter heart valve in patients with a failing mitral bioprosthetic valve....

Active, not recruiting

Mitral Valve Disease

Heart Failure

Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX

Edwards Lifesciences

Saint Louis, Missouri, United States and 11 other locations

ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting

Pulmonary Disease

Congenital Heart Disease

Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV

Edwards Lifesciences

Saint Louis, Missouri, United States and 13 other locations

Harmony TPV Post-Approval Study

The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...

Enrolling

Congenital Heart Disease

Tetrology of Fallot

Device: Harmony TPV System

Covidien

Saint Louis, Missouri, United States and 18 other locations

Distal Evaluation of Functional Performance With Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting (DEFINE GPS)

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only

Ischemic Heart Disease

Coronary Artery Disease

Device: Philips SyncVision system with Philips pressure wires

Procedure: standard of care angiographically-guided PCI