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of MAS825, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 28 people with known coronary heart...
Phase 2
Saint Louis, Missouri, United States and 5 other locations
is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart...
Phase 2
Saint Louis, Missouri, United States and 64 other locations
The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...
Saint Louis, Missouri, United States and 10 other locations
The goal of this clinical trial is to validate performance claims for method comparison for ABL90 FLEX PLUS in heparinized neonatal arterial, venous,...
Saint Louis, Missouri, United States
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (...
Saint Louis, Missouri, United States and 20 other locations
To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...
Saint Louis, Missouri, United States and 13 other locations
To assess the safety and effectiveness of the SAPIEN 3 transcatheter heart valve in patients with a failing mitral bioprosthetic valve....
Saint Louis, Missouri, United States and 11 other locations
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...
Phase 3
Saint Louis, Missouri, United States and 27 other locations
Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...
Saint Louis, Missouri, United States and 82 other locations
To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic...
Saint Louis, Missouri, United States and 29 other locations
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