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Find clinical trials for Kidney Disease in Ann Arbor, MI

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Carcinoma

Kidney Disease trials near Ann Arbor, MI, USA:

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...

Enrolling
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Drug: Tolvaptan (OPC-41061)

Phase 3

Otsuka
Otsuka

Ann Arbor, Michigan, United States and 17 other locations

This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...

Enrolling
Chronic Kidney Disease
Drug: Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD
Drug: Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD

Phase 2

Mineralys Therapeutics

Pontiac, Michigan, United States and 40 other locations

Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...

Enrolling
Chronic Kidney Disease; Iron Deficiency Anemia
Drug: Iron sucrose
Drug: Ferumoxytol

Phase 3

AMAG Pharmaceuticals
AMAG Pharmaceuticals

Detroit, Michigan, United States and 20 other locations

To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)* To characterize the pharmacokinetic (PK) properties of RGLS...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: RGLS8429
Drug: Placebo

Phase 1

Regulus Therapeutics

Roseville, Michigan, United States of America and 27 other locations

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Enrolling
Chronic Kidney Disease
Overweight
Drug: Placebo
Drug: Tirzepatide

Phase 2

Lilly
Lilly

Troy, Michigan, United States and 27 other locations

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Ann Arbor, Michigan, United States and 45 other locations

Locations recently updated

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Pontiac, Michigan, United States and 338 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: Placebo
Drug: DISC-0974

Phase 1

Disc Medicine

Saint Clair Shores, Michigan, United States and 10 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Troy, Michigan, United States and 70 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Ann Arbor, Michigan, United States and 241 other locations

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