Find clinical trials for Kidney Disease in Ann Arbor, MI

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Related conditions:

Kidney Diseases

Chronic Renal Insufficiency

Chronic Kidney Failure

IGA Glomerulonephritis

Renal Cell Carcinoma

Renal Insufficiency

Carcinoma

Kidney Disease trials near Ann Arbor, MI, USA:

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...

Enrolling

Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Drug: Tolvaptan (OPC-41061)

Phase 3

Otsuka

Ann Arbor, Michigan, United States and 17 other locations

Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects with Hypertension and Chronic Kidney Disease (CKD) with Albuminuria

This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...

Enrolling

Chronic Kidney Disease

Drug: Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD

Drug: Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD

Phase 2

Mineralys Therapeutics

Pontiac, Michigan, United States and 43 other locations

A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)

Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...

Enrolling

Chronic Kidney Disease; Iron Deficiency Anemia

Drug: Iron sucrose

Drug: Ferumoxytol

Phase 3

AMAG Pharmaceuticals

Detroit, Michigan, United States and 20 other locations

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)* To characterize the pharmacokinetic (PK) properties of RGLS...

Enrolling

Polycystic Kidney, Autosomal Dominant

Autosomal Dominant Polycystic Kidney Disease

Drug: Placebo

Drug: RGLS8429

Phase 1

Regulus Therapeutics

Roseville, Michigan, United States of America and 27 other locations

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes (TREASURE-CKD)

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Enrolling

Chronic Kidney Disease

Overweight

Drug: Placebo

Drug: Tirzepatide

Phase 2

Lilly

Troy, Michigan, United States and 27 other locations

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting

Chronic Kidney Disease With High Proteinuria

Drug: Dapagliflozin

Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca

Troy, Michigan, United States and 295 other locations

A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling

Chronic Kidney Diseases

Type 2 Diabetes Mellitus

Biological: Renal Autologous Cell Therapy (REACT)

Procedure: Sham Comparator

Phase 3

Prokidney

Ann Arbor, Michigan, United States and 55 other locations

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants with CKD and Anemia

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling

Anemia of Chronic Kidney Disease

Chronic Kidney Diseases

Drug: DISC-0974

Drug: Placebo

Phase 1

Disc Medicine

Saint Clair Shores, Michigan, United States and 11 other locations

A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.

safety, tolerability and the pharmacodynamics (PD) of AZD4144 following oral administration in participants with atherosclerotic cardiovascular disease...

Not yet enrolling

Chronic Kidney Disease

Atherosclerotic Cardiovascular Disease

Drug: AZD4144

Other: Placebo

Phase 1

AstraZeneca

Farmington Hills, Michigan, United States and 17 other locations

A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

The primary objective of this study is to evaluate the safety of tolvaptan in pediatric subjects with autosomal recessive polycystic kidney ...

Enrolling

Autosomal Recessive Polycystic Kidney (ARPKD)

Drug: Tolvaptan Suspension

Drug: Tolvaptan Tablets

Phase 3

Otsuka

Ann Arbor, Michigan, United States and 27 other locations

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Find clinical trials for Kidney Disease in .css-epvm6{white-space:nowrap;}Ann Arbor, MI

Related conditions:

Kidney Disease trials near Ann Arbor, MI, USA:

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects with Hypertension and Chronic Kidney Disease (CKD) with Albuminuria

A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes (TREASURE-CKD)

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants with CKD and Anemia

A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.

A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Find clinical trials for Kidney Disease in Ann Arbor, MI