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will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney...
Phase 3
Baltimore, Maryland, United States and 12 other locations
in the treatment of adult participants with a diagnosis of Diabetic Kidney Disease due to either Type 1 diabetes mellitus or Type 2...
Phase 2
Rockville, Maryland, United States and 71 other locations
is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...
Phase 3
Baltimore, Maryland, United States and 17 other locations
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...
Phase 3
Washington, District of Columbia, United States and 12 other locations
The aim of this Phase 2 study is to evaluate the safety and efficacy of the live biotherapeutic product, KT-301 (formerly US-APR2020), in the managem...
Phase 2
Silver Spring, Maryland, United States and 4 other locations
A) or REGN5458 (Part B) as monotherapy in patients with chronic kidney disease (CKD) who need kidney transplantation and a...
Phase 1, Phase 2
Baltimore, Maryland, United States and 7 other locations
ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...
Phase 1
Baltimore, Maryland, United States and 27 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Silver Spring, Maryland, United States and 321 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Takoma Park, Maryland, United States and 45 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Baltimore, Maryland, United States and 236 other locations
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