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have CKD, only approximately 10% of patients are aware of their kidney disease. In its 2020 Standards of Medical Care in Diabetes, ...
Boston, Massachusetts, United States
This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor [ASI]) for the treatment of hypertension...
Phase 2
Boston, Massachusetts, United States and 28 other locations
Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...
Phase 3
Boston, Massachusetts, United States and 18 other locations
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...
Phase 3
Boston, Massachusetts, United States and 12 other locations
ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...
Phase 1
Boston, Massachusetts, United States and 27 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Providence, Rhode Island, United States and 45 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Boston, Massachusetts, United States and 236 other locations
evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...
Phase 2
Providence, Rhode Island, United States and 70 other locations
Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...
Phase 3
Boston, Massachusetts, United States and 312 other locations
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys...
Phase 3
Boston, Massachusetts, United States and 80 other locations
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