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The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...
Phase 3
Charlotte, North Carolina, United States and 12 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Statesville, North Carolina, United States and 338 other locations
pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 in participants with chronic kidney...
Phase 2
Charlotte, North Carolina, United States and 25 other locations
evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...
Phase 2
Charlotte, North Carolina, United States and 70 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Charlotte, North Carolina, United States of America and 243 other locations
This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double blind, placebo controlled study. Part 1 (phase 2b) is a do...
Phase 2, Phase 3
Charlotte, North Carolina, United States and 70 other locations
(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...
Phase 3
Charlotte, North Carolina, United States and 944 other locations
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...
Phase 3
Statesville, North Carolina, United States and 581 other locations
This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...
Phase 3
Charlotte, North Carolina, United States and 68 other locations
This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...
Phase 3
Charlotte, North Carolina, United States and 67 other locations
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