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Find clinical trials for Kidney Disease in Charlotte, NC

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Related conditions:

Chronic Renal Insufficiency
Kidney Diseases
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Charlotte, NC, USA:

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Shelby, North Carolina, United States and 87 other locations

Locations recently updated

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Enrolling
APOL1-Mediated Kidney Disease
Combination Product: AZD2373-Arm 2
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Gastonia, North Carolina, United States and 88 other locations

Locations recently updated

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Charlotte, North Carolina, United States and 330 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 297 other locations

Locations recently updated

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 751 other locations

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Active, not recruiting
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

Phase 3

Novo Nordisk
Novo Nordisk

Charlotte, North Carolina, United States and 1072 other locations

Locations recently updated

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.This s...

Active, not recruiting
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 565 other locations

Locations recently updated

This study is open to adults with chronic kidney disease at risk of progression. People with and without type 2 diabetes can take p...

Enrolling
Kidney Disease, Chronic
Drug: Placebo matching BI 690517
Drug: BI 690517

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Charlotte, North Carolina, United States and 481 other locations

IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with ...

Enrolling
Chronic Kidney Disease(CKD)
Type 2 DM
Other: (IRIS-CKD Screening Program): Home Kit
Other: (IRIS-CKD Screening Program): Standard Lab Order
Duke University
Duke University

Houston, North Carolina, United States and 6 other locations

This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a...

Enrolling
Chronic Kidney Diseases
End Stage Renal Disease
Device: SelfWrap Bioabsorbable Perivascular Wrap
Procedure: Untreated AVF Control
VenoStent

Charlotte, North Carolina, United States and 29 other locations

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