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Find clinical trials for Kidney Disease in Charlotte, NC

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Charlotte, NC, USA:

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Shelby, North Carolina, United States and 55 other locations

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Enrolling
APOL1-Mediated Kidney Disease
Combination Product: Placebo
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Gastonia, North Carolina, United States and 71 other locations

Locations recently updated

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Charlotte, North Carolina, United States and 326 other locations

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...

Active, not recruiting
Chronic Kidney Disease (CKD)
Secondary Hyperparathyroidism (SHPT)
Drug: Paricalcitol

Phase 3

AbbVie
AbbVie

Charlotte, North Carolina, United States and 14 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 295 other locations

CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...

Active, not recruiting
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Charlotte, North Carolina, United States and 48 other locations

Locations recently updated

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 705 other locations

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Active, not recruiting
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

Phase 3

Novo Nordisk
Novo Nordisk

Charlotte, North Carolina, United States and 855 other locations

This study is open to adults with chronic kidney disease at risk of progression. People with and without type 2 diabetes can take p...

Enrolling
Kidney Disease, Chronic
Drug: Placebo matching BI 690517
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Charlotte, North Carolina, United States and 188 other locations

with end stage kidney disease (ESKD) undergoing maintenance dialysis....

Enrolling
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
Drug: CSL300
Drug: Placebo

Phase 2, Phase 3

CSL Behring
CSL Behring

Charlotte, North Carolina, United States and 356 other locations

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