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Find clinical trials for Kidney Disease in Charlotte, NC

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Charlotte, NC, USA:

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...

Enrolling
Chronic Kidney Disease (CKD)
Secondary Hyperparathyroidism (SHPT)
Drug: Paricalcitol

Phase 3

AbbVie
AbbVie

Charlotte, North Carolina, United States and 13 other locations

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 295 other locations

A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP (TRANQUILITY)

CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...

Active, not recruiting
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Charlotte, North Carolina, United States and 48 other locations

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure (BaxDuo-Pacific)

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 642 other locations

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease (AMPLITUDE)

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Charlotte, North Carolina, United States of America and 305 other locations

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

with end stage kidney disease (ESKD) undergoing maintenance dialysis....

Enrolling
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
Drug: CSL300
Drug: Placebo

Phase 2, Phase 3

CSL Behring
CSL Behring

Charlotte, North Carolina, United States and 250 other locations

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Active, not recruiting
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

Phase 3

Novo Nordisk
Novo Nordisk

Charlotte, North Carolina, United States and 850 other locations

Locations recently updated

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.This s...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 618 other locations

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2 (PATH-2)

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Active, not recruiting
End Stage Kidney Disease
Secondary Hyperparathyroidism
Drug: Open-Label Extension PLS240
Drug: PLS240

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 67 other locations

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Active, not recruiting
End-stage Kidney Disease (ESKD)
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Placebo

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 67 other locations

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