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Find clinical trials for Kidney Disease in Charlotte, NC

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Charlotte, NC, USA:

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...

Enrolling
Chronic Kidney Disease (CKD)
Secondary Hyperparathyroidism (SHPT)
Drug: Paricalcitol

Phase 3

AbbVie
AbbVie

Charlotte, North Carolina, United States and 12 other locations

pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 in participants with chronic kidney...

Enrolling
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Charlotte, North Carolina, United States and 15 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 70 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Charlotte, North Carolina, United States of America and 236 other locations

Recently updated

This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double blind, placebo controlled study. Part 1 (phase 2b) is a do...

Invitation-only
Atherosclerotic Cardiovascular Disease
End Stage Kidney Disease
Drug: CSL300
Drug: Placebo

Phase 2, Phase 3

CSL Behring
CSL Behring

Charlotte, North Carolina, United States and 60 other locations

Locations recently updated

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Enrolling
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

Phase 3

Novo Nordisk
Novo Nordisk

Charlotte, North Carolina, United States and 944 other locations

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 568 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Enrolling
End Stage Kidney Disease
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Placebo

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 68 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Enrolling
End-stage Kidney Disease (ESKD)
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Open-Label Extension PLS240

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 67 other locations

This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a...

Enrolling
Chronic Kidney Diseases
End Stage Renal Disease
Device: SelfWrap Bioabsorbable Perivascular Wrap
Procedure: Untreated AVF Control
VenoStent

Charlotte, North Carolina, United States and 6 other locations

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