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Find clinical trials for Kidney Disease in Charlotte, NC

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Charlotte, NC, USA:

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of...

Enrolling
Chronic Kidney Disease (CKD)
Secondary Hyperparathyroidism (SHPT)
Drug: Paricalcitol

Phase 3

AbbVie
AbbVie

Charlotte, North Carolina, United States and 12 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 338 other locations

CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...

Enrolling
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Charlotte, North Carolina, United States and 41 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Charlotte, North Carolina, United States of America and 280 other locations

This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double blind, placebo controlled study. Part 1 (phase 2b) is a do...

Enrolling
Atherosclerotic Cardiovascular Disease
End Stage Kidney Disease
Drug: CSL300
Drug: Placebo

Phase 2, Phase 3

CSL Behring
CSL Behring

Charlotte, North Carolina, United States and 120 other locations

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Enrolling
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

Phase 3

Novo Nordisk
Novo Nordisk

Charlotte, North Carolina, United States and 950 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Active, not recruiting
End Stage Kidney Disease
Secondary Hyperparathyroidism
Drug: Open-Label Extension PLS240
Drug: PLS240

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 67 other locations

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Statesville, North Carolina, United States and 591 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Active, not recruiting
End-stage Kidney Disease (ESKD)
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Placebo

Phase 3

Pathalys Pharma

Charlotte, North Carolina, United States and 67 other locations

This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a...

Enrolling
Chronic Kidney Diseases
End Stage Renal Disease
Device: SelfWrap Bioabsorbable Perivascular Wrap
Procedure: Untreated AVF Control
VenoStent

Charlotte, North Carolina, United States and 9 other locations

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