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in the treatment of adult participants with a diagnosis of Diabetic Kidney Disease due to either Type 1 diabetes mellitus or Type 2...
Phase 2
Chicago, Illinois, United States of America and 71 other locations
is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...
Phase 3
Chicago, Illinois, United States and 17 other locations
Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...
Phase 3
Chicago, Illinois, United States and 18 other locations
A) or REGN5458 (Part B) as monotherapy in patients with chronic kidney disease (CKD) who need kidney transplantation and a...
Phase 1, Phase 2
Chicago, Illinois, United States and 7 other locations
ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...
Phase 1
Chicago, Illinois, United States and 27 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Chicago, Illinois, United States and 321 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Chicago, Illinois, United States and 45 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Evergreen Park, Illinois, United States and 236 other locations
The primary objective of this study is to evaluate the safety of tolvaptan in pediatric subjects with autosomal recessive polycystic kidney ...
Phase 3
Chicago, Illinois, United States and 18 other locations
Primary Objective:Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH).Secondary Objectives:Eva...
Phase 3
Chicago, Illinois, United States and 29 other locations
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