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Find clinical trials for Kidney Disease in Columbus, OH

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Columbus, OH, USA:

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: DISC-0974
Drug: Placebo

Phase 1

Disc Medicine

Columbus, Ohio, United States and 10 other locations

pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 in participants with chronic kidney...

Enrolling
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Marion, Ohio, United States and 32 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Columbus, Ohio, United States and 280 other locations

The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Columbus, Ohio, United States and 186 other locations

This study is open to adults with a type of kidney disease called focal segmental glomerulosclerosis (FSGS). The purpose of this st...

Enrolling
Kidney Disease, Chronic
Drug: BI 764198
Drug: Placebo

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Columbus, Ohio, United States and 52 other locations

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Columbus, Ohio, United States and 591 other locations

The objective of this study is to establish that the MB-102 transdermal fluorescence-measured Glomerular Filtration Rate (GFR) using the MediBeacon®...

Active, not recruiting
Kidney Failure
Kidney Diseases
Device: MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
Drug: MB-102

Phase 3

MediBeacon

Columbus, Ohio, United States and 4 other locations

This is a Phase 2, Multi-center, Open-Label Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of R3R01 in Alport Syndrome Patients...

Enrolling
Alport Syndrome
Focal Segmental Glomerulosclerosis
Drug: R3R01

Phase 2

River 3 Renal

Columbus, Ohio, United States and 24 other locations

The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in...

Enrolling
Chronic Kidney Diseases
Cardiovascular Diseases
Device: Renal Denervation (Symplicity Spyral™)
Medtronic
Medtronic

Columbus, Ohio, United States and 91 other locations

of ravulizumab compared with placebo to reduce proteinuria and slow the rate of eGFR decline in adult participants with IgAN who are at risk of disease...

Enrolling
Immunoglobulin A Nephropathy
IgAN
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Columbus, Ohio, United States and 292 other locations

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