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Find clinical trials for Kidney Disease in Columbus, OH

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Columbus, OH, USA:

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Columbus, Ohio, United States and 87 other locations

study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney...

Enrolling
Complement-mediated Kidney Disease
IgA Nephropathy (IgAN)
Drug: ADX-038 Dose Level 1
Drug: ADX-038 Dose Level 2

Phase 2

ADARx Pharmaceuticals

Columbus, Ohio, United States and 24 other locations

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Enrolling
APOL1-Mediated Kidney Disease
Combination Product: Placebo
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Columbus, Ohio, United States and 76 other locations

baxdrostat in combination with dapagliflozin compared with baxdrostat/placebo on albuminuria, as well as safety, in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Baxdrostat/Placebo

Phase 2

AstraZeneca
AstraZeneca

Columbus, Ohio, United States and 70 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Columbus, Ohio, United States and 330 other locations

This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medici...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Columbus, Ohio, United States and 103 other locations

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Columbus, Ohio, United States and 744 other locations

The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...

Active, not recruiting
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Columbus, Ohio, United States and 161 other locations

This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resis...

Enrolling
Proteinuric Kidney Diseases
Drug: Placebo matching BI 764198
Drug: BI 764198

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Columbus, Ohio, United States and 146 other locations

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Finerenone (Kerendia, BAY94-8862)
Drug: Placebo

Phase 3

Bayer
Bayer

Columbus, Ohio, United States and 165 other locations

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