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Find clinical trials for Kidney Disease in Columbus, OH

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Columbus, OH, USA:

A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP (TRANQUILITY)

pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 in participants with chronic kidney...

Enrolling
Kidney Insufficiency, Chronic
Chronic Kidney Diseases
Drug: TOUR006 - 25 MG
Drug: TOUR006 - 50 MG

Phase 2

Tourmaline Bio

Marion, Ohio, United States and 15 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: Placebo
Drug: DISC-0974

Phase 1

Disc Medicine

Columbus, Ohio, United States and 10 other locations

Locations recently updated

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Columbus, Ohio, United States and 239 other locations

The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Columbus, Ohio, United States and 177 other locations

receptor is known to trigger injury and inflammation in the kidney and is therefore thought to play a role in CKD.Empagliflozin lowers blood...

Enrolling
Chronic Kidney Disease
Type 2 Diabetes Mellitus
Drug: Finerenone (BAY94-8862 ) 20 mg
Drug: Finerenone Placebo

Phase 2

Bayer
Bayer

Columbus, Ohio, United States and 210 other locations

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Placebo
Drug: Finerenone (Kerendia, BAY94-8862)

Phase 3

Bayer
Bayer

Columbus, Ohio, United States and 147 other locations

This study is open to adults with a type of kidney disease called focal segmental glomerulosclerosis (FSGS). The purpose of this st...

Enrolling
Kidney Disease, Chronic
Drug: BI 764198
Drug: Placebo

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Columbus, Ohio, United States and 60 other locations

This is a phase 3, multi-center, randomized, double-blind, placebo-controlled study in children with stage 3-4 chronic kidney disease...

Enrolling
Chronic Kidney Disease stage3
Chronic Kidney Disease stage4
Drug: Placebo
Drug: CTAP101

Phase 3

OPKO Health
OPKO Health

Columbus, Ohio, United States

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Columbus, Ohio, United States and 568 other locations

The objective of this study is to establish that the MB-102 transdermal fluorescence-measured Glomerular Filtration Rate (GFR) using the MediBeacon®...

Enrolling
Kidney Failure
Kidney Diseases
Device: MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
Drug: MB-102

Phase 3

MediBeacon

Columbus, Ohio, United States and 4 other locations

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