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This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Columbus, Ohio, United States and 55 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Columbus, Ohio, United States and 325 other locations
This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medici...
Phase 3
Columbus, Ohio, United States and 93 other locations
safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...
Phase 1
Columbus, Ohio, United States and 11 other locations
CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...
Phase 2
Marion, Ohio, United States and 48 other locations
and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...
Phase 3
Columbus, Ohio, United States and 700 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Columbus, Ohio, United States and 171 other locations
with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Columbus, Ohio, United States and 356 other locations
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.This s...
Phase 3
Columbus, Ohio, United States and 617 other locations
This is a Phase 2, Multi-center, Open-Label Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of R3R01 in Alport Syndrome Patients...
Phase 2
Columbus, Ohio, United States and 21 other locations
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