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safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...
Phase 1
Columbus, Ohio, United States and 11 other locations
CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney...
Phase 2
Marion, Ohio, United States and 41 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Columbus, Ohio, United States and 290 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Columbus, Ohio, United States and 191 other locations
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney...
Phase 3
Columbus, Ohio, United States and 129 other locations
This study is open to adults with a type of kidney disease called focal segmental glomerulosclerosis (FSGS). The purpose of this st...
Phase 2
Columbus, Ohio, United States and 49 other locations
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...
Phase 3
Columbus, Ohio, United States and 591 other locations
The objective of this study is to establish that the MB-102 transdermal fluorescence-measured Glomerular Filtration Rate (GFR) using the MediBeacon®...
Phase 3
Columbus, Ohio, United States and 4 other locations
This is a Phase 2, Multi-center, Open-Label Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of R3R01 in Alport Syndrome Patients...
Phase 2
Columbus, Ohio, United States and 24 other locations
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in...
Columbus, Ohio, United States and 94 other locations
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