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Find clinical trials for Kidney Disease in Detroit, MI

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Detroit, MI, USA:

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor \[ASI\]) for the treatment of hypertensi...

Enrolling
Chronic Kidney Disease
Drug: Part A - Lorundrostat QD + Dapaglifozin QD
Drug: Part A - Lorundrostat QD

Phase 2

Mineralys Therapeutics

Pontiac, Michigan, United States and 28 other locations

is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...

Enrolling
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Drug: Tolvaptan (OPC-41061)

Phase 3

Otsuka
Otsuka

Ann Arbor, Michigan, United States and 17 other locations

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors ...

Not yet enrolling
Kidney Failure, Chronic
Diabetic Nephropathies
Drug: Sotagliflozin
Drug: Placebo

Phase 3

Alessandro Doria

Ann Arbor, Michigan, United States and 18 other locations

Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...

Enrolling
Chronic Kidney Disease; Iron Deficiency Anemia
Drug: Iron sucrose
Drug: Ferumoxytol

Phase 3

AMAG Pharmaceuticals
AMAG Pharmaceuticals

Detroit, Michigan, United States and 20 other locations

To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)* To characterize the pharmacokinetic (PK) properties of RGLS...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: RGLS8429
Drug: Placebo

Phase 1

Regulus Therapeutics

Roseville, Michigan, United States of America and 27 other locations

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Enrolling
Chronic Kidney Disease
Overweight
Drug: Placebo
Drug: Tirzepatide

Phase 2

Lilly
Lilly

Troy, Michigan, United States and 27 other locations

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Roseville, Michigan, United States of America and 45 other locations

Locations recently updated

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Troy, Michigan, United States and 331 other locations

safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...

Enrolling
Anemia of Chronic Kidney Disease
Chronic Kidney Diseases
Drug: Placebo
Drug: DISC-0974

Phase 1

Disc Medicine

Saint Clair Shores, Michigan, United States and 10 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Troy, Michigan, United States and 70 other locations

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