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is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney...
Phase 3
Ann Arbor, Michigan, United States and 17 other locations
This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...
Phase 2
Pontiac, Michigan, United States and 43 other locations
Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...
Phase 3
Detroit, Michigan, United States and 20 other locations
To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)* To characterize the pharmacokinetic (PK) properties of RGLS...
Phase 1
Roseville, Michigan, United States of America and 27 other locations
We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...
Phase 2
Troy, Michigan, United States and 27 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Troy, Michigan, United States and 295 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Roseville, Michigan, United States of America and 55 other locations
safety, tolerability and the pharmacodynamics (PD) of AZD4144 following oral administration in participants with atherosclerotic cardiovascular disease...
Phase 1
Farmington Hills, Michigan, United States and 17 other locations
safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney...
Phase 1
Saint Clair Shores, Michigan, United States and 11 other locations
The primary objective of this study is to evaluate the safety of tolvaptan in pediatric subjects with autosomal recessive polycystic kidney ...
Phase 3
Ann Arbor, Michigan, United States and 27 other locations
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