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The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Dearborn, Michigan, United States and 85 other locations
study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney...
Phase 2
Shelby, Michigan, United States and 37 other locations
This study is researching an experimental drug called ALN-ANG3 (called "study drug"). The study is focused on participants who have diabetic kidney...
Phase 2
Pontiac, Michigan, United States and 59 other locations
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...
Phase 2
Shelby, Michigan, United States and 92 other locations
The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...
Phase 2
Roseville, Michigan, United States and 62 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Detroit, Michigan, United States and 330 other locations
with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Part...
Phase 3
Windsor, Canada and 561 other locations
Primary Objectives:To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemi...
Phase 3
Detroit, Michigan, United States and 20 other locations
Additionally, the study investigates the non-interventional feasibility of home measurement of serum creatinine in participants with diabetic kidney...
Phase 1
Ann Arbor, Michigan, United States and 5 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Troy, Michigan, United States and 297 other locations
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