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The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Durham, North Carolina, United States and 85 other locations
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that caus...
Phase 2
Chapel Hill, North Carolina, United States and 92 other locations
The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...
Phase 2
Durham, North Carolina, United States and 88 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Durham, North Carolina, United States and 330 other locations
The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.
Phase 3
Chapel Hill, North Carolina, United States and 89 other locations
and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...
Phase 3
Raleigh, North Carolina, United States and 757 other locations
This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resis...
Phase 2
Durham, North Carolina, United States and 162 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Raleigh, North Carolina, United States and 762 other locations
disease (ASCVD) or diabetes with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Durham, North Carolina, United States and 555 other locations
The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood...
Chapel Hill, North Carolina, United States and 18 other locations
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