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This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Durham, North Carolina, United States and 55 other locations
purpose of the study is to evaluate the efficacy, safety, and tolerability of Inaxaplin (IXP) in participants with proteinuric APOL1- mediated kidney...
Phase 2
Chapel Hill, North Carolina, United States and 33 other locations
The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...
Phase 2
Durham, North Carolina, United States and 76 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Durham, North Carolina, United States and 328 other locations
in African American/Blacks with APOL1- associated focal segmental glomerulosclerosis (FSGS) and non-diabetic APOL1-associated chronic kidney ...
Phase 2
Durham, North Carolina, United States
This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific t ...
Phase 2
Durham, North Carolina, United States of America and 163 other locations
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Chapel Hill, North Carolina, United States and 81 other locations
Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...
Phase 3
Chapel Hill, North Carolina, United States and 339 other locations
and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...
Phase 3
Raleigh, North Carolina, United States and 705 other locations
of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...
Phase 3
Raleigh, North Carolina, United States and 826 other locations
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