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This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Greensboro, North Carolina, United States and 21 other locations
in African American/Blacks with APOL1- associated focal segmental glomerulosclerosis (FSGS) and non-diabetic APOL1-associated chronic kidney ...
Phase 2
Durham, North Carolina, United States
of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...
Phase 3
Chapel Hill, North Carolina, United States and 55 other locations
Primary Objective:Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH).Secondary Objectives:* E...
Phase 3
Durham, North Carolina, United States and 29 other locations
Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...
Phase 3
Chapel Hill, North Carolina, United States and 339 other locations
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys...
Phase 3
Chapel Hill, North Carolina, United States and 86 other locations
tolerability and pharmacokinetics (PK) of VX-147 in participants aged 18 years and older with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 3
Durham, North Carolina, United States and 302 other locations
receptor is known to trigger injury and inflammation in the kidney and is therefore thought to play a role in CKD.Empagliflozin lowers blood...
Phase 2
Chapel Hill, North Carolina, United States and 189 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Durham, North Carolina, United States and 206 other locations
with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Durham, North Carolina, United States and 197 other locations
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