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Find clinical trials for Kidney Disease in Houston, TX

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Houston, TX, USA:

A Phase 2 Study of MZE829 in Adults with APOL1 Kidney Disease

This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Houston, Texas, United States and 21 other locations

Status recently updated

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Not yet enrolling
Enrolling
APOL1-Mediated Kidney Disease
Combination Product: Placebo
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Pearland, Texas, United States and 31 other locations

Chronic kidney disease CKD is estimated to affect nearly over 800 million people globally today (with roughly 125,000 people ending....

Begins enrollment in 6 months
Kidney Failure
Chronic Kidney Diseases
Drug: QRX-3

Phase 2, Phase 3

Ebima Clifford Okundaye

Pasadena, Texas, United States

This is a randomized, double-blind (DB), placebo controlled, crossover study with a two-period, two-sequence (2x2) design evaluating the efficacy and...

Active, not recruiting
Chronic Kidney Disease
Drug: Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD
Drug: Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD

Phase 2

Mineralys Therapeutics

Katy, Texas, United States and 43 other locations

purpose of the study is to evaluate the efficacy, safety, and tolerability of Inaxaplin (IXP) in participants with proteinuric APOL1- mediated kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Inaxaplin

Phase 2

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Houston, Texas, United States of America and 11 other locations

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Not yet enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Houston, Texas, United States and 319 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Active, not recruiting
Chronic Kidney Disease With High Proteinuria
Drug: Dapagliflozin
Drug: Zibotentan/Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Houston, Texas, United States and 295 other locations

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Houston, Texas, United States and 55 other locations

compared with dapagliflozin alone on patients with chronic kidney disease (CKD) and albuminuria. This study will evaluate the effec...

Active, not recruiting
Chronic Kidney Disease
Drug: Dapagliflozin 10 mg and matching placebo for balcinrenone/dapa gliflozin
Drug: Balcinrenone/dapagliflozin 40 mg/10 mg and matching placebo for dapagliflozin 10 mg

Phase 2

AstraZeneca
AstraZeneca

Houston, Texas, United States and 92 other locations

Primary Objective:Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH).Secondary Objectives:* E...

Active, not recruiting
Secondary Hyperparathyroidism-Chronic Kidney Disease
Drug: Doxercalciferol (GZ427397)
Drug: Calcitriol

Phase 3

Sanofi
Sanofi

Houston, Texas, United States and 29 other locations

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