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Find clinical trials for Kidney Disease in Indianapolis, IN

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Indianapolis, IN, USA:

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes (TREASURE-CKD)

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Enrolling
Chronic Kidney Disease
Overweight
Drug: Placebo
Drug: Tirzepatide

Phase 2

Lilly
Lilly

Indianapolis, Indiana, United States and 28 other locations

Locations recently updated

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Indianapolis, Indiana, United States and 231 other locations

Primary Objective:Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH).Secondary Objectives:Eva...

Active, not recruiting
Secondary Hyperparathyroidism-Chronic Kidney Disease
Drug: Doxercalciferol (GZ427397)
Drug: Calcitriol

Phase 3

Sanofi
Sanofi

Indianapolis, Indiana, United States and 29 other locations

evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney...

Active, not recruiting
Chronic Kidney Diseases
Uncontrolled Hypertension
Drug: Placebo
Drug: CIN-107

Phase 2

AstraZeneca
AstraZeneca

Brownsburg, Indiana, United States and 70 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Enrolling
End-stage Kidney Disease (ESKD)
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Open-Label Extension PLS240

Phase 3

Pathalys Pharma

Shelbyville, Indiana, United States and 66 other locations

dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpo...

Active, not recruiting
Disease Progression
Iron
Drug: Placebo
Drug: Ferric Citrate 1 GM Oral Tablet [AURYXIA]

Phase 3

USRC Kidney Research

Shelbyville, Indiana, United States and 22 other locations

The main purpose is to determine the safety of Triferic iron administered via dialysate and intravenously in pediatric patients with chronic kidney...

Enrolling
End Stage Renal Disease
Drug: Triferic

Phase 3

Rockwell Medical

Indianapolis, Indiana, United States and 8 other locations

The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in...

Enrolling
Chronic Kidney Diseases
Cardiovascular Diseases
Device: Renal Denervation (Symplicity Spyral™)
Medtronic
Medtronic

Indianapolis, Indiana, United States and 78 other locations

HAV and AVF groups over 12 months in patients with end-stage renal disease (ESRD) needing hemodialysis (HD).Participants will be stratified ...

Enrolling
End Stage Renal Disease (ESRD)
Biological: HAV
Other: AVF

Phase 3

Humacyte
Humacyte

Bloomington, Indiana, United States and 16 other locations

The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...

Enrolling
Chronic Kidney Disease
Cardiovascular Diseases
Drug: Orforglipron
Drug: Insulin Glargine

Phase 3

Lilly
Lilly

Avon, Indiana, United States and 390 other locations

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