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Find clinical trials for Kidney Disease in Indianapolis, IN

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Cell Carcinoma
Renal Insufficiency
Carcinoma

Kidney Disease trials near Indianapolis, IN, USA:

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes (TREASURE-CKD)

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Enrolling
Chronic Kidney Disease
Overweight
Drug: Placebo
Drug: Tirzepatide

Phase 2

Lilly
Lilly

Indianapolis, Indiana, United States and 27 other locations

Primary Objective:Evaluate the effect of Hectorol® capsules in reducing elevated levels of intact parathyroid hormone (iPTH).Secondary Objectives:* E...

Active, not recruiting
Secondary Hyperparathyroidism-Chronic Kidney Disease
Drug: Doxercalciferol (GZ427397)
Drug: Calcitriol

Phase 3

Sanofi
Sanofi

Indianapolis, Indiana, United States and 29 other locations

The primary objective of this study is to evaluate the safety of tolvaptan in pediatric subjects with autosomal recessive polycystic kidney ...

Enrolling
Autosomal Recessive Polycystic Kidney (ARPKD)
Drug: Tolvaptan Suspension
Drug: Tolvaptan Tablets

Phase 3

Otsuka
Otsuka

Indianapolis, Indiana, United States and 27 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Indianapolis, Indiana, United States and 290 other locations

Locations recently updated

The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...

Enrolling
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Indianapolis, Indiana, United States and 191 other locations

function in participants with overweight or obesity and chronic kidney disease (CKD), with or without Type 2 Diabetes (T2D). The st...

Enrolling
Overweight or Obesity
CKD
Drug: Placebo
Drug: Retatrutide

Phase 2

Lilly
Lilly

Indianapolis, Indiana, United States and 38 other locations

This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD)...

Active, not recruiting
End-stage Kidney Disease (ESKD)
Secondary Hyperparathyroidism
Drug: PLS240
Drug: Placebo

Phase 3

Pathalys Pharma

Shelbyville, Indiana, United States and 67 other locations

of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...

Enrolling
Overweight and Obesity
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Indianapolis, Indiana, United States and 707 other locations

A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.

Enrolling
X-linked Hypophosphatemia
Drug: KK8123

Phase 1, Phase 2

Kyowa Kirin
Kyowa Kirin

Indianapolis, Indiana, United States and 8 other locations

Locations recently updated

The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in...

Enrolling
Chronic Kidney Diseases
Cardiovascular Diseases
Device: Renal Denervation (Symplicity Spyral™)
Medtronic
Medtronic

Indianapolis, Indiana, United States and 94 other locations

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