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Find clinical trials for Kidney Disease in Indianapolis, IN

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Related conditions:

Chronic Renal Insufficiency
Kidney Diseases
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Kidney Cancer

Kidney Disease trials near Indianapolis, IN, USA:

Locations recently updated

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease (AMPLITUDE)

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Indianapolis, Indiana, United States and 330 other locations

This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medici...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Indianapolis, Indiana, United States and 103 other locations

We are doing this study to learn more about how tirzepatide may help fight chronic kidney disease in people with obesity with or wi...

Active, not recruiting
Chronic Kidney Disease
Overweight
Drug: Placebo
Drug: Tirzepatide

Phase 2

Lilly
Lilly

Indianapolis, Indiana, United States and 26 other locations

To evaluate the safety of tolvaptan in pediatric subjects with ARPKD

Enrolling
Autosomal Recessive Polycystic Kidney (ARPKD)
Drug: Tolvaptan Tablets
Drug: Tolvaptan Suspension

Phase 3

Otsuka
Otsuka

Indianapolis, Indiana, United States and 22 other locations

The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT/ rilparencel)
Procedure: Sham Comparator

Phase 3

Prokidney

Fishers, Indiana, United States and 96 other locations

Locations recently updated

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Indianapolis, Indiana, United States and 751 other locations

of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Indianapolis, Indiana, United States and 762 other locations

The purpose of this study is to determine if BHV-1400 is a safe and tolerable treatment in participants with IgA Nephropathy (IgAN).

Enrolling
IgA Nephropathy
Drug: BHV-1400

Phase 1

Biohaven
Biohaven

Indianapolis, Indiana, United States and 14 other locations

A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.

Enrolling
X-linked Hypophosphatemia
Drug: KK8123

Phase 1, Phase 2

Kyowa Kirin
Kyowa Kirin

Indianapolis, Indiana, United States and 8 other locations

The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in...

Active, not recruiting
Chronic Kidney Diseases
Cardiovascular Diseases
Device: Renal Denervation (Symplicity Spyral™)
Medtronic
Medtronic

Indianapolis, Indiana, United States and 100 other locations

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