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Find clinical trials for Kidney Disease in Jacksonville, FL

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
Renal Insufficiency
IGA Glomerulonephritis
Renal Cell Carcinoma
Diabetes Mellitus

Kidney Disease trials near Jacksonville, FL, USA:

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

ObjectivesTo assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV)To characterize the pharmacokinetic (PK) properties...

Enrolling
Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease
Drug: RGLS8429
Drug: Placebo

Phase 1

Regulus Therapeutics

Jacksonville, Florida, United States and 27 other locations

to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...

Enrolling
Chronic Kidney Disease With High Proteinuria
Drug: Zibotentan/Dapagliflozin
Drug: Dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Jacksonville, Florida, United States and 321 other locations

This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2...

Enrolling
Chronic Kidney Disease
Obesity
Drug: Semaglutide
Drug: Placebo

Phase 2

Novo Nordisk
Novo Nordisk

Orlando, Florida, United States and 100 other locations

receptor is known to trigger injury and inflammation in the kidney and is therefore thought to play a role in CKD.Empagliflozin lowers blood...

Enrolling
Chronic Kidney Disease
Type 2 Diabetes Mellitus
Drug: Finerenone (BAY94-8862 ) 20 mg
Drug: Empagliflozin Placebo

Phase 2

Bayer
Bayer

Jacksonville, Florida, United States and 210 other locations

(for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.Parti...

Enrolling
Chronic Kidney Disease
Inflammation
Drug: Ziltivekimab C
Drug: Placebo (Ziltivekimab B)

Phase 3

Novo Nordisk
Novo Nordisk

Jacksonville, Florida, United States and 943 other locations

The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Dapagliflozin in combination with placebo

Phase 3

AstraZeneca
AstraZeneca

Jacksonville, Florida, United States and 559 other locations

The primary aim of the study is to investigate the effect of empagliflozin on kidney disease progression or cardiovascular death ve ...

Active, not recruiting
Chronic Kidney Disease
Drug: Matching placebo
Drug: Empagliflozin

Phase 3

Boehringer Ingelheim
Boehringer Ingelheim

Jacksonville, Florida, United States of America and 239 other locations

The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in peop...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Saint Augustine, Florida, United States and 405 other locations

of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/ ...

Not yet enrolling
Overweight and Obesity
Drug: Placebo
Drug: Retatrutide

Phase 3

Lilly
Lilly

Fleming Island, Florida, United States and 348 other locations

The proposed clinical study is a prospective, non-randomized, multi-center, single-arm, observational, post-market surveillance (PS) study of the Ell...

Active, not recruiting
Kidney Disease, End-Stage
Renal Disease, End Stage
Device: Ellipsys Vascular Access System
Medtronic
Medtronic

Jacksonville, Florida, United States and 11 other locations

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